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  • Keeps Cells Younger for Longer
  • Promotes Cells Renewal
  • Reverses DNA Damage & Prevents Cutaneous Ageing
  • Combats Sagging Skin & Provide a Lifting Effect
  • Diminishes Fine Lines & Wrinkles
  • Reduces Pigmentation Irregularities & Provides Radiance
  • Increases the Skin Resistance
  • Protects the Cells Against Free Radicals

Description

This product is on sale due to it being short dated 30/07/2025

The first of its kind in the world!        

DNA research has finally made it possible to turn back the clock on all the ageing effects caused by environmental factors.

This science-driven cream is the fruit of years of research and development. It rejuvenates cells, improves the skin's elasticity and plumpness, reduces pigmentation and restructures the facial contours like no other.

La Grande Crème contains the greatest number of concentrated active ingredients ever used in a Biologique Recherche product. Epigenetic research (the study of genes) enabled scientists to identify the properties of EpigenActiv© in an anti-ageing skincare product. This peptide acts on Epidermal Growth Factor (EGF) receptors.

This pioneering cream, tackles all age-related phenomena and will leave your skin toned, smooth, protected, radiant and even.

Active Ingredients

  • Regenerating Agents: EpigenActiv©, Milk Thistle Extract & Mimosa Extract
  • Structuring Agent: Peony Extract
  • Firming Agent: Complex of Elderflower, Chestnut Tree, and Myrobalan Leaf Extracts
  • Anti-Wrinkle Agents: Complex of Matrikines, Myorelaxant Peptides, and Carcinine
  • Anti-Spot Agents: White Tea Extract, Watercress Sprout Extract & Soy-Based Pure Genistein
  • Protective Agents: Oligosaccharides, Pichia Anomala Extract, Wasabi Extract & Grape Juice Extract (enriched with δ-Viniferin)

See full inci list here

Skin Type

Ideal for mature skins. Perfect for skins in need of rejuvenation.

How to Use

Apply a hazelnut-sized amount of La Grande Crème in the morning and/or evening to the cleansed skin of entire face, neck, and décolleté. Massage the product into the skin, using upward strokes.

Media

How To Apply La Grande Crème
Guide to Growth Factors

OUTLET | La Grande Crème

Biologique Recherche

OUTLET | La Grande Crème

Biologique Recherche
This product is on sale due to it being short dated 30/07/2025. The Biologique Recherche La Grande Crème is an advanced anti-ageing cream formulated to reverse signs of ageing. It harnesses potent actives to promote cellular regeneration, repair DNA damage, and leave skin brighter, firmer, and protected.
£836 £929
Size
You could earn EB Points from this product.
Learn More

Actions

  • Keeps Cells Younger for Longer
  • Promotes Cells Renewal
  • Reverses DNA Damage & Prevents Cutaneous Ageing
  • Combats Sagging Skin & Provide a Lifting Effect
  • Diminishes Fine Lines & Wrinkles
  • Reduces Pigmentation Irregularities & Provides Radiance
  • Increases the Skin Resistance
  • Protects the Cells Against Free Radicals

Description

This product is on sale due to it being short dated 30/07/2025

The first of its kind in the world!        

DNA research has finally made it possible to turn back the clock on all the ageing effects caused by environmental factors.

This science-driven cream is the fruit of years of research and development. It rejuvenates cells, improves the skin's elasticity and plumpness, reduces pigmentation and restructures the facial contours like no other.

La Grande Crème contains the greatest number of concentrated active ingredients ever used in a Biologique Recherche product. Epigenetic research (the study of genes) enabled scientists to identify the properties of EpigenActiv© in an anti-ageing skincare product. This peptide acts on Epidermal Growth Factor (EGF) receptors.

This pioneering cream, tackles all age-related phenomena and will leave your skin toned, smooth, protected, radiant and even.

Active Ingredients

  • Regenerating Agents: EpigenActiv©, Milk Thistle Extract & Mimosa Extract
  • Structuring Agent: Peony Extract
  • Firming Agent: Complex of Elderflower, Chestnut Tree, and Myrobalan Leaf Extracts
  • Anti-Wrinkle Agents: Complex of Matrikines, Myorelaxant Peptides, and Carcinine
  • Anti-Spot Agents: White Tea Extract, Watercress Sprout Extract & Soy-Based Pure Genistein
  • Protective Agents: Oligosaccharides, Pichia Anomala Extract, Wasabi Extract & Grape Juice Extract (enriched with δ-Viniferin)

See full inci list here

Skin Type

Ideal for mature skins. Perfect for skins in need of rejuvenation.

How to Use

Apply a hazelnut-sized amount of La Grande Crème in the morning and/or evening to the cleansed skin of entire face, neck, and décolleté. Massage the product into the skin, using upward strokes.

Media

How To Apply La Grande Crème
Guide to Growth Factors

MAKE SURE TO COMPLETE YOUR ROUTINE

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    Biologique Recherche Skincare La Grande Crème: most innovative anti-ageing facial cream.
    Biologique Recherche

    OUTLET | La Grande Crème

    £836 £929

    This product is on sale due to it being short dated 30/07/2025

    The first of its kind in the world!        

    DNA research has finally made it possible to turn back the clock on all the ageing effects caused by environmental factors.

    This science-driven cream is the fruit of years of research and development. It rejuvenates cells, improves the skin's elasticity and plumpness, reduces pigmentation and restructures the facial contours like no other.

    La Grande Crème contains the greatest number of concentrated active ingredients ever used in a Biologique Recherche product. Epigenetic research (the study of genes) enabled scientists to identify the properties of EpigenActiv© in an anti-ageing skincare product. This peptide acts on Epidermal Growth Factor (EGF) receptors.

    This pioneering cream, tackles all age-related phenomena and will leave your skin toned, smooth, protected, radiant and even.

    View product