Benefits
  • Anti-Ageing
  • Anti-Wrinkle
  • Firming
  • Plumping
  • Regenerating
  • Antioxidant
  • Anti-Inflammatory
Progeskin by Biologique Recherche fights the signs of ageing and skin senescence by targeting key proteins for ultimate rejuvenation. Defining facial features by delivering firmness, plumpness, smoothness and tone.
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Progeskin by Biologique Recherche fights the signs of ageing and skin senescence by targeting key proteins for ultimate rejuvenation. Defining facial features by delivering firmness, plumpness, smoothness and tone.
Read less
£158 £175
You could earn With this purchase

More Info

  • - + Who it is for
  • - + How to Apply
  • - + Smell & Texture
  • - + Ingredients
Who it is for
Green tick
For you if
  • Mature
  • Loss of Firmness
  • Wrinkles
  • Delay Skin Ageing
Red Cross
Not For you if
  • Unbalanced
How to Apply
Lightly massage 10 drops of Progeskin into clean skin over the entire face, neck and décolleté until the product has been completely absorbed.
Smell & Texture

Smells Like: A neutral scent with hints of botanical notes.

Texture: Lightweight and watery consistency.

Ingredients

Water (Aqua), Propylene Glycol, Glycerin, Methylpropanediol, Ethoxydiglycol, Centaurea Cyanus Flower Extract, Juglans Regia (Walnut) Seed Extract, Juglans Regia (Walnut) Shell Extract, Trifluoroacetyl Tripeptide-2, Xanthan Gum, Dextran, Disodium EDTA, Caprylyl Glycol, Benzoic Acid, Sodium Metabisulfite, Sorbic Acid.

The Benefits

Anti-Ageing (Senescence)

The advancement in anti-ageing skincare now enables us to combat cellular senescence—a state where cells stop dividing but remain metabolically active, continuing processes like protein synthesis. This means that while these cells no longer contribute to tissue renewal, they still engage in metabolic activities, producing proteins and other molecules that can affect the surrounding tissue. Skin senescence is triggered by factors such as stress, poor diet, lack of sleep, DNA damage, inflammation, and genetic predisposition. Over time, the accumulation of these senescent cells accelerates ageing by secreting harmful compounds that cause inflammation and damage surrounding tissues and cells. Innovative technologies in anti-ageing skincare can now target cellular senescence using advanced actives to inhibit senescence-associated markers and promote cell regeneration. By regenerating skin cells, these products reduce visible signs of ageing, such as wrinkles, sagging, and discoloration, while enhancing skin resilience and overall health.

Anti-Wrinkle

Anti-wrinkle products work to smooth out fine lines and wrinkles by boosting collagen and elastin, essential proteins that keep your skin glowing. Collagen helps reduce wrinkle depth, while elastin shortens their length. Keeping your skin hydrated is crucial, as dehydration can make wrinkles more noticeable. For smooth, bouncy skin, ensure you stay well-hydrated and use products that promote collagen and elastin production.

Firming

Skin firming focuses on boosting your skin's elasticity and tightness to reduce sagging and wrinkles, leaving your skin looking firmer. This is done by stimulating fibroblasts to produce more elastin, the protein that helps your skin stretch and bounce back. To keep your skin firm longer, antioxidants protect these elastin fibres from free radical damage, which can cause early breakdown. This combined action helps maintain a youthful, resilient complexion.

Plumping

Skin plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction, and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

Photo-Protecting

Photo-protective products offer strong protection against harmful UV radiation. They create a defensive barrier on your skin, preventing sunburn, premature ageing, and DNA damage from sun exposure. These products help reduce the risk of photoageing, including fine lines, wrinkles, and dark spots, while also supporting your skin’s natural repair processes to minimize the impact of any existing sun damage.

Regenerating

Regenerative benefits work to restore and renew your skin at a cellular level. By stimulating cell turnover and boosting collagen and elastin production, they help repair damage, diminish fine lines and wrinkles, and improve overall skin texture. The result is a rejuvenated, firmer, and more youthful complexion that radiates vitality.

Antioxidant

Antioxidant Protection shields your skin and preserves its youthful glow. It refers to a defence system that protects against harmful molecules and keeps your complexion healthy and radiant. Free radicals, those incredibly reactive molecules, come from everyday sources like sunlight, diet, smoking, and pollution. They attack healthy cells, accelerating skin ageing, causing wrinkles, loss of firmness, pigmentation, and dullness.

Incorporating antioxidants, such as vitamins C and E, into your skincare routine creates a protective shield on your skin. These powerful ingredients neutralise free radicals, preventing them from causing damage. The result is skin that stays youthful, firm, and luminous.

Anti-Inflammatory

Anti-Inflammatory skincare soothes, heal, and balance your skin, the targeted actives are designed to reduce inflammation. Inflammation is your body's natural response to injury or irritation, but continuous inflammation can lead to troublesome skin conditions like acne, rosacea, or eczema. Our anti-inflammatory skincare solutions work to soothe and calm your skin, reducing redness, swelling, and discomfort to provide much-needed relief. By strengthening your skin's barrier, these products help protect against further irritation and damage. Additionally, the anti-inflammatory actives support your skin's natural healing processes, leading to a more balanced and resilient complexion.

  • - + Anti-Ageing (Senescence)
  • - + Anti-Wrinkle
  • - + Firming
  • - + Plumping
  • - + Photo-Protecting
  • - + Regenerating
  • - + Antioxidant
  • - + Anti-Inflammatory

Active Ingredients

Progescence

Progescence® is a powerful tripeptide with exceptional anti-ageing properties. It targets progerin, a protein that accumulates with age and indicates cellular senescence. By reducing progerin synthesis, Progescence® effectively diminishes visible signs of ageing, such as wrinkles, sagging and loss of tone. Additionally, it stimulates collagen production, enhancing elasticity and plumpness for a smoother, more contoured facial appearance.

Pro-KL

Pro-KL® is a cutting-edge active ingredient that works by activating the Klotho protein. This helps to regulate cell metabolism, delaying the onset of senescence in skin cells and promoting their longevity. This protective action combats the effects of ageing while maintaining the skin structure by preserving collagen and elastin fibres. As a result, Pro-KL® restructures and firms the skin. Additionally, its antioxidant and anti-inflammatory properties strengthen your skin barrier and protection against external damage

  • - + Progescence
  • - + Pro-KL

Spotlight

Senescence

Advancements in anti-aging skincare now focus on targeting cellular senescence, a state where cells lose their ability to divide but remain metabolically active. Although senescent cells no longer contribute to tissue repair or renewal, they persist in synthesizing proteins and signaling molecules that can negatively impact surrounding tissues through the senescence-associated secretory phenotype (SASP). SASP includes pro-inflammatory cytokines, matrix-degrading enzymes, and growth factors that disrupt the extracellular matrix, promote chronic inflammation, and accelerate skin aging. Skin senescence is triggered by intrinsic and extrinsic factors, including oxidative stress, UV-induced DNA damage, inflammation, poor lifestyle choices, and genetic predisposition. Over time, the accumulation of senescent cells contributes to visible aging signs such as wrinkles, sagging, and hyperpigmentation by impairing skin structure and function. Innovative anti-aging technologies now incorporate active compounds that inhibit markers of senescence, such as p16INK4a and p21, while promoting cell regeneration and reducing SASP activity. Ingredients like retinoids, peptides, antioxidants, and senolytics are employed to stimulate cellular turnover, repair damage, and reduce inflammation. These advanced formulations work to restore skin resilience, enhance elasticity, and minimize aging signs, providing a scientific approach to healthier, more youthful skin.

Why I love it

  • "The efficacy of Biologique Recherche relies not only on its science-driven approach to balancing and curing the skin, but on its prescriptive and tailored nature."

    X Natalie K-F

    Founder, Embassy of Beauty

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    Biologique Recherche

    Progeskin

    £158 £175
    Introducing Progeskin, a groundbreaking serum which defies the visible signs of skin senescence, designed to slow skin aging. Its advanced technology contains 2 main formulations; Progescence®, which reduces the accumulation of senescent cells over time & Pro-KL®, which delays skin senescence.

    They target two essential proteins: progerin, linked to skin ageing, and Klotho, known as the "youth protein." Progeskin works by reducing progerin production while boosting Klotho levels, leading to delayed ageing, fewer wrinkles, and a more youthful complexion. The key ingredient, Progescence—a specialised tripeptide—supports your skin’s natural repair process, enhancing its resilience. 

    This innovative serum offers multiple benefits; it promotes cell renewal and boosts collagen production, ensuring your skin remains firm, smooth, and radiant, with wrinkles significantly reduced. It stimulates cell renewal for a brighter complexion, and it reduces oxidative stress, protecting your skin from premature ageing. Additionally, Progeskin also strengthens your skin barrier, enhancing moisture retention and shielding against external damage, thanks to the Klotho protein's crucial role.
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