Prebiotic Regenerating Night Cream
Benefits
The Demain Beauty Prebiotic Regenerating Night Cream is a deeply nourishing overnight treatment that targets wrinkles, loss of firmness and cellular fatigue, combining a collagen-stimulating active complex with a restorative oil blend, microbiome-rebalancing ferments and a natural endorphin-activating fragrance to work in synchrony with the skin's own nocturnal repair cycle.
Lactococcus Ferment Lysate and Leuconostoc Radish Root Ferment Filtrate form the pre and postbiotic microbiome complex — the ferment lysate stimulates collagen synthesis, improves skin elasticity, firms and redensifies the dermis while oxygenating cells for a visibly brighter complexion, while the radish root ferment rebalances and reinforces the skin's bacterial ecosystem throughout the night.
Sodium Hyaluronate and Saccharide Isomerate form the core hydrating duo — Hyaluronic Acid plumps the epidermis from within, visibly reducing wrinkle depth and restoring suppleness overnight, while Saccharide Isomerate mimics the skin's own natural hydration factors for lasting, deeply anchored hydration that persists into the following morning.
Milk Thistle Oil and Shea Butter form the restorative nourishing complex — Milk Thistle, rich in over 70% unsaturated fatty acids, actively supports cellular reconstitution and barrier repair overnight, while Shea Butter deeply nourishes, softens and protects with its concentrated blend of vitamins A, E and F.
Ribose energises skin cells at a mitochondrial level to support overnight renewal, Jania Rubens (Red Algae) Extract delivers a concentrated marine mineral boost to revitalise and firm, and Lavandula Stoechas (Lavender) Extract calms and soothes, while Tocopherol, Beta-Sitosterol and Chlorella Vulgaris provide a final layer of antioxidant and barrier protection.
The Demain Beauty Prebiotic Regenerating Night Cream is a deeply nourishing overnight treatment that targets wrinkles, loss of firmness and cellular fatigue, combining a collagen-stimulating active complex with a restorative oil blend, microbiome-rebalancing ferments and a natural endorphin-activating fragrance to work in synchrony with the skin's own nocturnal repair cycle.
Lactococcus Ferment Lysate and Leuconostoc Radish Root Ferment Filtrate form the pre and postbiotic microbiome complex — the ferment lysate stimulates collagen synthesis, improves skin elasticity, firms and redensifies the dermis while oxygenating cells for a visibly brighter complexion, while the radish root ferment rebalances and reinforces the skin's bacterial ecosystem throughout the night.
Sodium Hyaluronate and Saccharide Isomerate form the core hydrating duo — Hyaluronic Acid plumps the epidermis from within, visibly reducing wrinkle depth and restoring suppleness overnight, while Saccharide Isomerate mimics the skin's own natural hydration factors for lasting, deeply anchored hydration that persists into the following morning.
Milk Thistle Oil and Shea Butter form the restorative nourishing complex — Milk Thistle, rich in over 70% unsaturated fatty acids, actively supports cellular reconstitution and barrier repair overnight, while Shea Butter deeply nourishes, softens and protects with its concentrated blend of vitamins A, E and F.
Ribose energises skin cells at a mitochondrial level to support overnight renewal, Jania Rubens (Red Algae) Extract delivers a concentrated marine mineral boost to revitalise and firm, and Lavandula Stoechas (Lavender) Extract calms and soothes, while Tocopherol, Beta-Sitosterol and Chlorella Vulgaris provide a final layer of antioxidant and barrier protection.
Read less40 ml
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Is this for you?
For you if
- Disrupted Microbiome
- Wrinkles
- Loss of Volume
- Loss of Firmness
- Dehydration
- Fine Lines
- Damaged Barrier
- Dryness
Suitable for
- Reactive Skin
- Sensitive Skin
- Dehydrated Skin
- Eczema & Psoriasis
- Dry Skin
- Rosacea
- Balanced Skin
Not for you if
How to apply
Core Routine
- First Cleanse
- Second Cleanse
- Toner
- Hydrating Serum
- Targeted Serum
- Cream / Facial Oil
Period after opening
Extended Routine
- Eye Cleanse
- First Cleanse
- Second Cleanse
- Toner (Non-Exfoliating)
- Toner (Exfoliating)
- Mask
- Hydrating Serum
- Targeted Serum
- Eye Care
- Cream / Facial Oil
- SPF
Ingredients
Lactococcus Ferment Lysate (Probiotic)Microbiome Balancing
Fermented Lactococcus Ferment Lysate is derived from the fermentation of the Lactococcus Lactis bacteria. This process releases natural sugars that serve as probiotics on the skin, enhancing the balance of the skin microbiome. It promotes the growth of beneficial microorganisms while safeguarding against harmful bacteria. In addition to supporting the microbiome, it functions as a natural preservative and skin softener.RiboseAnti-Wrinkle · Plumping · Firming & Lifting
Ribose works in precise synchrony with the skin's own circadian rhythm — boosting the energy available for collagen production, accelerating cellular turnover and supporting the structural processes that restore firmness, elasticity and radiance from within.Radish Root FermentMicrobiome Balancing
Radish Root Ferment acts as a targeted prebiotic — selectively feeding and strengthening beneficial bacteria on the skin's surface while simultaneously inhibiting the growth of pathogenic microorganisms. This dual action supports a more balanced, diverse and resilient skin microbiome, creating the conditions in which the skin's own natural defence and repair mechanisms can function optimally.Low Molecular Weight Hyaluronic AcidPlumping · Hydrating
Low Molecular Weight Hyaluronic Acid (LMW-HA) is a smaller, more penetrative form of hyaluronic acid. Unlike high molecular weight forms that primarily hydrate the skin’s surface, LMW-HA has the ability to penetrate deeper into the epidermis, where it attracts and binds water to maintain optimal moisture levels from within. This deep hydration helps improve skin elasticity, firmness and smoothness, while reducing the appearance of fine lines. Additionally, it enhances overall suppleness, making the complexion look plumper and more resilient. It is ideal for dehydrated, dull or mature skin, and especially those in need of long-lasting hydration and improved texture.Saccharide Isomerate (PENTAVITIN)Microbiome Balancing · Hydrating · Reduces Trans Epidermal Water Loss
Saccharide Isomerate, also known as PentavitinÆ, is a carbohydrate complex derived from plants that closely resembles those found in human skin. It serves multiple functions in skincare: first, it acts as a prebiotic, supporting a healthy balance of microorganisms on the skin's surface, which is crucial for maintaining skin health.
Secondly, Saccharide Isomerate functions as a powerful humectant. This means it attracts moisture from the environment and binds it to the skin, acting like a "water magnet." This ability helps to deeply hydrate the skin, making it appear plump, smooth, and intensely moisturised.
Studies have shown that Saccharide Isomerate can increase skin hydration levels for up to 72 hours after application, making it an effective ingredient for providing long-lasting hydration and maintaining skin moisture balance.Milk Thistle OilSkin Barrier Strengthening · Antioxidant · Nourishing
Milk Thistle Oil actively supports cellular reconstitution and barrier repair, replenishing the skin's hydrolipidic film and restoring elasticity and suppleness to skin that has become dry, depleted or visibly aged. Its high Vitamin E content neutralises free radical damage and protects against environmental oxidative stress, while its omega 6 fatty acids deeply nourish and strengthen the skin's natural resilience over time.Shea ButterNourishing
Shea Butter is renowned for its deeply nourishing benefits. It helps to repair and strengthen a weakened skin barrier while enhancing water retention. It quickly replenishes and restores dry, dehydrated and fragile skins.Algae ExtractAnti-Wrinkle · Plumping · Hydrating
Algae Extract is a nutrient-dense marine active, rich in antioxidants, amino acids, and essential minerals that help protect skin from environmental damage. Its high antioxidant capacity neutralises free radicals generated by UV exposure and pollution, reducing oxidative stress that accelerates skin ageing. Naturally hydrating polysaccharides draw and retain moisture, reinforcing the skin barrier and improving elasticity. The combination of protective and replenishing actions helps maintain a smoother, more resilient, and plumper complexion.Red Algae ExtractAnti-Wrinkle · Firming & Lifting · Reduces Trans Epidermal Water Loss
Red Algae Extract actively supports collagen and elastin synthesis, helping to firm, redensify and restore structural integrity to skin that has lost elasticity and tone with age or environmental damage. Its polysaccharide content forms a breathable, protective film on the skin's surface that locks in hydration, reinforces barrier function and shields against transepidermal water loss, while its naturally occurring antioxidants neutralise free radical damage and protect against the oxidative stress that accelerates visible ageing.
View full ingredient list
Smell & Texture
Delivery & Returns
ROYAL MAIL TRACKED 48:
£5.00 (free for members on orders over £75)
Delivered within 2-3 working days.
NEXT WORKING DAY DELIVERY:
£8.00 (free for members on orders over £150)
Delivered the next working day if ordered before 1pm.
SATURDAY UK DELIVERY:
£18.00
Delivered on Saturday when ordered before 1pm on Friday.
*(For NI, Channel Islands & Scotland - due to the courier service in place, we cannot guarantee next day delivery to these areas, however we expect you will receive your delivery within 2-5 days).
RETURNS
Items returned by post can take up to 14 working days to process. Credit notes can be applied to your account within 5 working days. For refunds, we will reimburse you using your original payment method which can take up to 14 days.
The Benefits
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Microbiome Balancing
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Anti-Wrinkle
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Plumping
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Firming & Lifting
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Hydrating
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Reduces Trans Epidermal Water Loss
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Skin Barrier Strengthening
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Antioxidant
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Nourishing
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Photo-Protecting
Microbiome Balancing
Anti-Wrinkle
Plumping
Firming & Lifting
Hydrating
Reduces Trans Epidermal Water Loss
Skin Barrier Strengthening
Antioxidant
Nourishing
Photo-Protecting
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Microbiome Balancing
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Anti-Wrinkle
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Plumping
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Firming & Lifting
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Hydrating
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Reduces Trans Epidermal Water Loss
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Skin Barrier Strengthening
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Antioxidant
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Nourishing
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Photo-Protecting
Spotlight
Pre, Pro & Postbiotics
Frequently Asked Questions
Where do I use this cream in my routine?
Can I use this cream if I have oily skin?
Can I use this cream if I have dry skin?
Can I use this cream if I have acne prone skin?
Can I use this product if I have sensitive skin?
Can I use this product if I have rosacea?
Is this cream Anti-Ageing?
Why I love it
X Natalie K-F
Founder, Embassy of Beauty






