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Creme Dermopurifiante

(10)
PURIFY & REFRESH
Creme Dermopurifiante
Biologique Recherche
(10)
Benefits
  • Anti-Bacterial
  • Anti-Acne
  • Anti-Inflammatory
  • Mattifying
  • Microbiome Balancing
  • Complexion-Unifying
  • Purifying
  • Detoxifying
  • Clears Pores
  • Barrier-Strengthening
  • Anti-Wrinkle
  • Firming
  • Lifting
  • Plumping
  • Regenerating
  • Scar-Repairing
  • Brightening
  • Anti-Redness
  • Antioxidant

Biologique Recherche Creme Dermopurifiante is a purifying and reparative treatment cream that not only regulates sebum and prevents congestion but also actively supports post-acne healing to reduce the risk of scarring.

Zinc and burdock extract provide antibacterial and sebum regulating action while calming inflammation at its source — a critical step in preventing post-inflammatory hyperpigmentation (PIH) and textural scarring.

Yeast and amino acid complexes accelerate cellular renewal, helping to fade residual marks left by breakouts and improve epidermal reconstruction.

Meanwhile, soothing actives help stabilise the barrier to limit micro-inflammation, ensuring clearer healing pathways.

Read more

Biologique Recherche Creme Dermopurifiante is a purifying and reparative treatment cream that not only regulates sebum and prevents congestion but also actively supports post-acne healing to reduce the risk of scarring.

Zinc and burdock extract provide antibacterial and sebum regulating action while calming inflammation at its source — a critical step in preventing post-inflammatory hyperpigmentation (PIH) and textural scarring.

Yeast and amino acid complexes accelerate cellular renewal, helping to fade residual marks left by breakouts and improve epidermal reconstruction.

Meanwhile, soothing actives help stabilise the barrier to limit micro-inflammation, ensuring clearer healing pathways.

Read less

50 ml

£130
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Get The Set
Biologique Recherche Acne Control & Balance Collection - Cream & Serum
Acne Control & Balance Collection

Creme Dermopurifiante
Complexe Iribiol Serum

£185 £175

More Info

  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
Who it is for
Green tick
For you if

Oily Skin

Active Acne

Enlarged Pores

Acne Pigmentation

Stressed Skin

Red Cross
Not For you if
How to Apply
Apply a hazelnut-sized amount of Crème Dermopurifiante to affected areas on the face.
Ingredients

Scroll down the page for a full breakdown of the active ingredients.

Water (Aqua), Glycerin, Propylene Glycol, Dicaprylyl Carbonate, Butylene Glycol, Sucrose Polystearate, C10-18 Triglycerides, Cetyl Alcohol, Glyceryl Stearate Citrate, Pentaerythrityl Tetra-stearate, 1,2-Hexanediol, Boron Nitride, Niacinamide, Betula Alba Bark Extract, Equisetum Arvense Extract, Arctium Lappa Root Extract, Enantia Chlorantha Bark Extract, Hedera Helix (Ivy) Leaf/Stem Extract, Fucus Vesiculosus Extract, Hydrolyzed Algin, Centella Asiatica Extract, Spiraea Ulmaria Extract, Arnica Montana Flower Extract, Rosa Canina Fruit Extract, Myrtus Communis Leaf Extract, Achillea Millefolium Extract, Aesculus Hippocastanum (Horse Chestnut) Seed Extract, Lavandula Angustifolia (Lavender) Flower Extract, Thymus Vulgaris (Thyme) Flower/Leaf/Stem Extract, Allium Cepa (Onion) Bulb Extract, Commiphora Myrrha Resin Extract, Oleanolic Acid, Yeast Extract, Citric Acid, Tocopherol, Caramel, Polyacrylate Crosspolymer-6, Zinc Sulfate, Caprylyl Glycol, Sodium Benzoate, Potassium Sorbate


Please note: The ingredients listed in this product are subject to change as the formulation is updated. We aim to update the INCI list as soon as possible, but we encourage you to read the ingredient list on the product itself to ensure it's suitable for your personal use.

Smell & Texture

Smells Like: A scent reminiscent of yeast, with earthy undertones.

Texture: A light, creamy and smooth texture

About the Brand
Brand logo
Founded in Paris in the late 1970s by biologist Yvan Allouche and physiotherapist Josette Allouche, Biologique Recherche began as a laboratory for bespoke, high-performance formulas for elite skin professionals. Their medical-grade precision and artisanal formulation, paired with consummate savoir-faire, underpin their reputation for outstanding, clinically proven results.

Biologique Recherche treats skin according to its Skin Instant©, the skin’s precise, evolving state. Each formula is loaded with active ingredients in exceptional concentrations, then prescribed to address those real-time needs. This precision approach corrects imbalances, restores function, and delivers visible, lasting transformation.

Cold-processed actives are the core of Biologique Recherche. Formulated at 18–25°C, this method avoids the 70°C heat of standard processing that breaks down actives. Botanical, marine, and biotechnological extracts stay intact for higher absorption, stronger repair, and better tolerance. Antioxidants, peptides, and enzymes remain stable, ensuring consistent, visible results.

The Benefits

  • - + Anti-Bacterial
  • - + Anti-Inflammatory
  • - + Sebum Regulating (Mattifying)
  • - + Microbiome Balancing
  • - + Complexion-Unifying (Anti-Blotchiness)
  • - + Purifying
  • - + Detoxifying
  • - + Pore Decongesting
  • - + Skin Barrier Strengthening
  • - + Anti-Wrinkle
  • - + Firming & Lifting
  • - + Plumping
  • - + Regenerating
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Anti-Redness
  • - + Antioxidant
Anti-Bacterial

Anti-bacterial action targets and inhibits the growth of bacteria on your skin's surface. Anti-bacterial ingredients work by disrupting essential bacterial processes like cell wall synthesis or protein production, reducing the risk of skin infections and inflammation. They are especially effective for treating acne by controlling the acne-causing bacteria known as Cutibacterium acnes (C. acnes). This anti-bacterial action helps diminish imperfections, prevent new breakouts, and reduce irritation, giving you clearer, healthier skin.

Anti-Inflammatory

Anti-Inflammatory skincare soothes, heal, and balance your skin, the targeted actives are designed to reduce inflammation. Inflammation is your body's natural response to injury or irritation, but continuous inflammation can lead to troublesome skin conditions like acne, rosacea, or eczema. Our anti-inflammatory skincare solutions work to soothe and calm your skin, reducing redness, swelling, and discomfort to provide much-needed relief. By strengthening your skin's barrier, these products help protect against further irritation and damage. Additionally, the anti-inflammatory actives support your skin's natural healing processes, leading to a more balanced and resilient complexion.

Sebum Regulating (Mattifying)

Sebum regulation involves normalising oil production in your sebaceous glands to reduce shine, oiliness and breakouts, restoring your skin's natural balance. Overactive sebaceous glands can be triggered by internal factors like genetics, hormonal changes and stress, as well as external factors such as using stripping or overly active skincare, climate, pollution and diet. Excessive sebum production can lead to enlarged pores, acne and an oily, shiny appearance. Effective sebum regulation means using skincare products that balance oil levels without over-drying your skin, helping you achieve a clearer, more matte complexion.

Microbiome Balancing

Microbiome Balancing skincare focuses on supporting the skin’s ecosystem through a precise combination of prebiotics, probiotics, and postbiotics—each playing a distinct and complementary role. Prebiotics act as a targeted nutrient source, feeding and promoting the growth of beneficial microorganisms to maintain balance within the skin’s microbiome. Probiotics then introduce and reinforce these beneficial bacteria, helping to strengthen the skin’s natural defenses and reduce the presence of harmful strains. Postbiotics, the bioactive compounds produced through this process, enhance overall skin function by supporting barrier strength, improving hydration, and calming inflammation. Together, this synergistic approach stabilises the skin environment, resulting in a complexion that is clearer, more resilient, and visibly healthier.

Complexion-Unifying (Anti-Blotchiness)

Evening skin tone is all about reducing blotchiness and achieving a more uniform complexion. Skincare products designed for this purpose use a blend of active ingredients, including soothing agents, anti-pigmentation compounds, antioxidants, and skin-restoring elements. These ingredients work together to diminish redness, inflammation, and pigment irregularities caused by inflammation, while also strengthening and protecting your skin against environmental irritants and future damage. This promotes healing and resilience, leaving your skin more balanced, radiant, and beautiful.

Purifying

Purifying skincare is designed to deeply cleanse and decongest the skin by targeting excess oil at its source—within the pores. Rather than simply removing surface shine, these formulations work to dissolve and dislodge sebum, debris, and impurities trapped inside the pore lining, helping to prevent congestion, blackheads, and breakouts. Actives such as exfoliating acids and oil-regulating ingredients penetrate into the pore to effectively “strip out” excess oil, restoring clarity and refining skin texture. By clearing buildup from within, purifying treatments leave the skin feeling exceptionally clean, balanced and visibly smoother.

Detoxifying

Detoxifying skincare focuses on clearing the skin of accumulated pollutants, toxins, and metabolic waste that can dull the complexion and disrupt healthy function. Daily exposure to environmental aggressors such as pollution and oxidative stress can overwhelm the skin, leading to congestion, imbalance, and premature ageing. Advanced detoxifying formulations work to neutralise these impurities, support the skin’s natural elimination processes, and reduce the buildup of harmful particles within pores and on the surface. By restoring clarity and balance, this approach leaves the skin feeling purified, refreshed and visibly brighter.

Pore Decongesting

Pore decongesting focuses on both clearing and minimising the appearance of enlarged pores. Enlarged pores often result from excess oil production and the build-up of impurities within the pore, which can stretch them over time, while ageing further contributes as reduced elasticity makes them more visible. Effective formulations work first to clear the pores—dissolving and removing trapped sebum, debris, and congestion—before regulating oil production and supporting collagen and elastin to improve skin firmness. By addressing both internal build-up and structural integrity, pores can return to a clearer, more refined, and less noticeable state.

Skin Barrier Strengthening

Strengthening your skin barrier involves replenishing the key elements in the top layer of your skin (stratum corneum), leading to a stronger and healthier barrier. These essential elements include lipids (ceramides, fatty acids, and cholesterol) and Natural Moisturizing Factors (amino acids, hyaluronic acid, etc.). Various factors, such as incorrect skincare use, seasonal changes, and aesthetic treatments, can damage your skin barrier. When this happens, your skin loses excess water through Trans Epidermal Water Loss (T.E.W.L) and becomes less capable of defending against environmental stressors, resulting in dryness, sensitivity, and irritation.

A healthy skin barrier is crucial for overall skin health as it helps prevent hydration loss, protects against environmental damage, and reduces the risk of skin conditions like eczema and acne. By strengthening your skin barrier, you ensure your skin remains well-hydrated, resilient, and protected.

Anti-Wrinkle

Anti-wrinkle skincare is focused on both preventing and visibly reducing the formation of lines by targeting the structural and dynamic causes of wrinkles within the skin. Fine lines and deeper wrinkles develop as collagen and elastin decline, cell turnover slows and repeated facial movements create creases that become etched over time. Advanced formulations address these mechanisms through a combination of elastin-stimulating actives, smoothing peptides that help relax the appearance of expression lines, and deeply hydrating ingredients that plump the skin from within. By reinforcing the skin’s architecture while softening surface contractions and improving elasticity, anti-wrinkle skincare delivers a visibly smoother complexion.

Firming & Lifting

Firming & Lifting skincare is designed to restore strength, structure, and definition to the skin, creating a visibly tighter, more sculpted appearance. As the skin loses collagen and elasticity over time, it can begin to soften and sag, losing its natural contours. Advanced formulations work to rebuild this support from within—boosting firmness while helping to visibly lift and redefine the skin. The result is a smoother, more toned complexion with enhanced bounce and resilience, where facial contours appear sharper and elevated.

Plumping

Plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

Regenerating

Regenerating skincare actively stimulates the formation of new, healthier skin, working in alignment with the skin’s innate renewal processes. Central to this are growth factors—effectively encouraging the development of new skin tissue. Peptides complement this by acting as targeted messengers guiding the skin to rebuild with greater strength and structural integrity. Stem cell–derived actives further support this environment by delivering protective and regenerative signals that optimize cellular function and renewal. While these mechanisms are synonymous with advanced anti-ageing—improving firmness, elasticity and overall skin quality—they are equally valuable in addressing scarring, as they promote tissue repair, accelerate regeneration and help restore a smoother, more even skin surface.

Scar-Repairing

Anti-Scarring skincare targets the textured scars left by acne breakouts. These scars form due to inflammation disrupting collagen and elastin fibres leading to uneven healing and indented areas. Anti-Scarring actives harness growth factors and exfoliating actives to stimulate cell repair and regeneration, optimising the skin's healing process to reduce scar formation. They also effectively diminish older scars, improving overall skin texture and leaving you with a smoother complexion and significantly reduced scar visibility.

Brightening (Energising)

Brightening skincare involves using active ingredients to boost your blood circulation, detoxification and cellular energy. Improved blood circulation brings more essential nutrients and oxygen to your skin, while detoxification helps eliminate cell waste and impurities that can make your skin look dull. Certain active ingredients also enhance your skin's metabolism and regeneration. These combined actions restore your skin's vitality and radiant appearance, giving you a fresh, energised complexion.

Anti-Redness

Anti-Redness skincare is all about reducing and preventing facial or body redness, which can result from irritation, skin conditions, compromised barriers, and hormonal changes. A targeted approach with multiple strategies works best for tackling redness. Anti-Redness formulations include active ingredients that soothe and strengthen your skin barrier. Their anti-inflammatory and antioxidant properties calm inflammation and protect against environmental irritants. Additionally, these ingredients have vasoconstrictive properties, meaning they reduce blood vessel dilation to lessen redness. Together, these actions help achieve a more even-toned, balanced complexion that's less prone to redness flare-ups.

Antioxidant

Antioxidant skincare is dedicated to protecting the skin against oxidative stress—one of the primary drivers of premature ageing and cellular damage—while preserving overall skin integrity and vitality. These formulations rely on potent molecules such as vitamin C, vitamin E, and polyphenols, which neutralize free radicals generated by UV exposure and environmental aggressors before they can compromise cellular structures like lipids, proteins, and DNA. Beyond defence, many antioxidants also support repair processes and enhance collagen stability, contributing to improved firmness, brightness and resilience. The result is skin that is not only shielded from ongoing damage but maintained in a healthier, more luminous state over time.

  • - + Anti-Bacterial
  • - + Anti-Inflammatory
  • - + Sebum Regulating (Mattifying)
  • - + Microbiome Balancing
  • - + Complexion-Unifying (Anti-Blotchiness)
  • - + Purifying
  • - + Detoxifying
  • - + Pore Decongesting
  • - + Skin Barrier Strengthening
  • - + Anti-Wrinkle
  • - + Firming & Lifting
  • - + Plumping
  • - + Regenerating
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Anti-Redness
  • - + Antioxidant

Active Ingredients

  • - + Complex of Brown Algae & Zinc
  • - + Yeast Extract
  • - + Complex of Enanthia Chlorantha & Oleanic Acid
  • - + Mimosa Tenuiflora Extract
  • - + Centella Asiatica
  • - + Vitamin B3 (Niacinamide)
  • - + Onion, Myrrh & Myrtle Extract
  • - + Arnica Extract
Complex of Brown Algae & Zinc

The Complex of Brown Algae & Zinc combines the anti-bacterial benefits of Zinc with the repairing and anti-inflammatory benefits of Brown Algae, extremely appropriate for acne-prone skin. The Complex decreases sebum secretion and limits acneic infections by inhibiting the growth of C. Acnes and S. Aureus bacteria. It also decreases inflammation and promotes the healing process.

Yeast Extract

Yeast extract is a bio-fermented active that helps rebalance the skin’s microbiome while regulating excess sebum and reducing congestion or dullness. By supporting a healthier microbial environment, it limits the growth of unwanted bacteria on the skin’s surface, helping to purify and refine texture without stripping or irritation. Its enzymatic action also encourages gentle cellular turnover, which helps lift away built-up dead skin cells and improves clarity, contributing to a brighter and more even complexion. Furthermore, yeast helps to reinforce barrier function so the skin remains more stable, resilient, and less reactive over time. This makes yeast extract especially effective for skin that is unbalanced, oily-tendency, stressed by urban pollution, or in need of both soothing repair and a clearer, healthier surface environment.

Complex of Enanthia Chlorantha & Oleanic Acid

The Complex of Enanthia Chlorantha & Oleanic Acid deactivates sebocytes, which are the cells in the sebaceous glands which contain oils. Oleanic Acid inhibits the formation of Dihydrotestosterone which deactivates the stimulation of the sebocytes. Whilst, Enantia complements this action by inhibiting the sebocytes' growth and slows down sebum (oil) secretion. The result is that the pores are less engorged with sebum, and less sebum is produced for a much more mattified complexion and tighter pores.

Mimosa Tenuiflora Extract

The Mimosa Tenuiflora Extract aids in stimulating tissue repair to regenerate new tissue and its anti-microbial & healing benefits protect and repair the skin.

Centella Asiatica

Centella Asiatica is a powerful antioxidant which has immense anti-inflammatory, soothing and wound-healing benefits. Rich in chlorophyll, it is also extremely proficient at reducing redness. Also known as "Tiger Grass" as tigers were known to roll in it after having been wounded.

Vitamin B3 (Niacinamide)

Vitamin B3 also known as Niacinamide, is versatile and highly effective ingredient with many benefits. It helps to strengthen skin barrier function and increase water retention by increasing natural ceramide production. It's anti-inflammatory and sebum regulating properties soothe, repair and balance irritated, weakened and acne prone skins. Niacinamide is also a potent antioxidant with protective and brightening properties helping to restore skin's natural glow.

Onion, Myrrh & Myrtle Extract

Unique to Biologique Recherche, the "Complex of Onion, Myrrh & Myrtle" has incredible astringent (tightening), purifying, antioxidant and soothing properties; which is very effective for an oilier complexion combatting sebum-regulation, acne or congestion.

Arnica Extract

Arnica Extract is rich in flavonoids and Phenolic Acid. It has powerful anti-inflammatory benefits, expert at protecting sensitive skin and soothing tightness. Arnica also contains strong antioxidant and protective benefits.

  • - + Complex of Brown Algae & Zinc
  • - + Yeast Extract
  • - + Complex of Enanthia Chlorantha & Oleanic Acid
  • - + Mimosa Tenuiflora Extract
  • - + Centella Asiatica
  • - + Vitamin B3 (Niacinamide)
  • - + Onion, Myrrh & Myrtle Extract
  • - + Arnica Extract
Active & Inflamed Acne

Acne affects more than 640 million people worldwide, around 85% of whom are teenagers. The primary reason for dermatological consultation is classified into two main categories: inflammatory acne and comedonal acne. There are 3 levels of severity, depending on the number, type and distribution of lesions, as well as the presence of scars. Classification helps determine the most suitable treatment for each case. Comedonal acne is mild and non-inflammatory, consisting of black and white heads, while moderate to severe acne is inflammatory and consists of papules, pustules, nodules and cysts which can be sore to the touch and typically red or swollen in appearance. Acne is a complex, multifactorial, chronic disease involving genetic, metabolic and hormonal factors, with cutaneous and gut microbiota playing a key role.

Clinical Proofs

EFFICACY TEST:
Test conducted on 20 women with combination to oily or oily skin, with shiny skin, dilated pores on the
cheeks and nasal wings, and redness or blemishes caused by acne. Measurements of the number of
sebaceous follicles were taken at the beginning of the study and after 28 days of applying the product
twice daily.
USAGE TEST:
Test conducted on 20 women with combination to oily or oily skin, with shiny skin, dilated pores on the
cheeks and nasal wings, and redness or blemishes caused by acne. The participants applied the product
twice daily for 28 days.
Results confirmed the product’s sebum regulating action. They showed:
- A significant decrease in the number of sebaceous follicles: -28%
- A regulating action vis-à-vis sebaceous secretions

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Spotlight

Active & Inflamed Acne

Acne affects more than 640 million people worldwide, around 85% of whom are teenagers. The primary reason for dermatological consultation is classified into two main categories: inflammatory acne and comedonal acne. There are 3 levels of severity, depending on the number, type and distribution of lesions, as well as the presence of scars. Classification helps determine the most suitable treatment for each case. Comedonal acne is mild and non-inflammatory, consisting of black and white heads, while moderate to severe acne is inflammatory and consists of papules, pustules, nodules and cysts which can be sore to the touch and typically red or swollen in appearance. Acne is a complex, multifactorial, chronic disease involving genetic, metabolic and hormonal factors, with cutaneous and gut microbiota playing a key role.

Clinical Proofs

Clinical Proofs

EFFICACY TEST:
Test conducted on 20 women with combination to oily or oily skin, with shiny skin, dilated pores on the
cheeks and nasal wings, and redness or blemishes caused by acne. Measurements of the number of
sebaceous follicles were taken at the beginning of the study and after 28 days of applying the product
twice daily.
USAGE TEST:
Test conducted on 20 women with combination to oily or oily skin, with shiny skin, dilated pores on the
cheeks and nasal wings, and redness or blemishes caused by acne. The participants applied the product
twice daily for 28 days.
Results confirmed the product’s sebum regulating action. They showed:
- A significant decrease in the number of sebaceous follicles: -28%
- A regulating action vis-à-vis sebaceous secretions

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Why I love it

  • "The efficacy of Biologique Recherche relies not only on its science-driven approach to balancing and curing the skin, but on its prescriptive and tailored nature."

    X Natalie K-F

    Founder, Embassy of Beauty

  • Biologique Recherche Creme Dermopurifiante 50ml
    Biologique Recherche

    Creme Dermopurifiante

    £130

    Biologique Recherche Creme Dermopurifiante is a purifying and reparative treatment cream that not only regulates sebum and prevents congestion but also actively supports post-acne healing to reduce the risk of scarring.

    Zinc and burdock extract provide antibacterial and sebum regulating action while calming inflammation at its source — a critical step in preventing post-inflammatory hyperpigmentation (PIH) and textural scarring.

    Yeast and amino acid complexes accelerate cellular renewal, helping to fade residual marks left by breakouts and improve epidermal reconstruction.

    Meanwhile, soothing actives help stabilise the barrier to limit micro-inflammation, ensuring clearer healing pathways.

    View product