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(7)
LINE REDUCING
(7)
Benefits
  • Cellular Anti-Ageing
  • Anti-Wrinkle
  • Regenerating
  • Barrier-Strengthening
  • Firming
  • Lifting
  • Plumping
  • Anti-Pigmentation
  • Scar-Repairing
  • Brightening

Biologique Recherche Serum A-Glyca combats ageing caused by glycation, preventing sugar from binding to collagen and elastin and protecting deep skin cells. It reduces deep lines and wrinkles, firms the skin and boosts radiance.

Mimosa Extract protects and repairs collagen and elastin fibres damaged by glycation, preserving the structural proteins that keep skin youthful, smooth, plump and taut. It progressively restores the integrity of the dermal matrix, improving firmness, elasticity and the skin's overall youthful appearance.

Carcinine is a powerful antioxidant dipeptide that scavenges advanced glycation end-products (AGEs) and protects cellular proteins from further glycation-related damage. Together, these two actives work to undo the yellowing, stiffening and loss of bounce associated with glycated skin, delivering a visibly firmer, brighter and more resilient complexion with continued use.

Read more

Biologique Recherche Serum A-Glyca combats ageing caused by glycation, preventing sugar from binding to collagen and elastin and protecting deep skin cells. It reduces deep lines and wrinkles, firms the skin and boosts radiance.

Mimosa Extract protects and repairs collagen and elastin fibres damaged by glycation, preserving the structural proteins that keep skin youthful, smooth, plump and taut. It progressively restores the integrity of the dermal matrix, improving firmness, elasticity and the skin's overall youthful appearance.

Carcinine is a powerful antioxidant dipeptide that scavenges advanced glycation end-products (AGEs) and protects cellular proteins from further glycation-related damage. Together, these two actives work to undo the yellowing, stiffening and loss of bounce associated with glycated skin, delivering a visibly firmer, brighter and more resilient complexion with continued use.

Read less

30 ml

£200
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Get The Set
Biologique Recherche Anti-Ageing Serum Collection
Anti-Ageing Serum Collection

Serum A-Glyca
Serum Elastine
Serum Collagene Originel

£525 £499

More Info

  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
Who it is for
Green tick
For you if

Wrinkles

Loss of Firmness

Loss of Tone

Antioxidant Support

Red Cross
Not For you if
How to Apply
Lightly massage 10 drops of Sérum A-Glyca into clean skin over the entire face, neck and décolleté until the product has been completely absorbed.
Ingredients

Scroll down the page for a full breakdown of the active ingredients.

Water (Aqua), Albizia Julibrissin Bark Extract, Glycerin, Propylene Glycol, Phenoxyethanol, Decarboxy Carnosine HCl, Papaver Rhoeas Flower Extract, Butylene Glycol, Ethylhexylglycerin, Sodium Benzoate


Please note: The ingredients listed in this product are subject to change as the formulation is updated. We aim to update the INCI list as soon as possible, but we encourage you to read the ingredient list on the product itself to ensure it's suitable for your personal use.

Smell & Texture

Smells Like: A neutral scent with hints of botanical notes.

Texture: Lightweight and watery consistency.

About the Brand
Brand logo
Founded in Paris in the late 1970s by biologist Yvan Allouche and physiotherapist Josette Allouche, Biologique Recherche began as a laboratory for bespoke, high-performance formulas for elite skin professionals. Their medical-grade precision and artisanal formulation, paired with consummate savoir-faire, underpin their reputation for outstanding, clinically proven results.

Biologique Recherche treats skin according to its Skin Instant©, the skin’s precise, evolving state. Each formula is loaded with active ingredients in exceptional concentrations, then prescribed to address those real-time needs. This precision approach corrects imbalances, restores function, and delivers visible, lasting transformation.

Cold-processed actives are the core of Biologique Recherche. Formulated at 18–25°C, this method avoids the 70°C heat of standard processing that breaks down actives. Botanical, marine, and biotechnological extracts stay intact for higher absorption, stronger repair, and better tolerance. Antioxidants, peptides, and enzymes remain stable, ensuring consistent, visible results.

The Benefits

  • - + Anti-Ageing (Glycation)
  • - + Anti-Wrinkle
  • - + Regenerating
  • - + Skin Barrier Strengthening
  • - + Firming & Lifting
  • - + Plumping
  • - + Anti-Pigmentation
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Prevents Collagen Breakdown
Anti-Ageing (Glycation)

Combat Glycation and maintain firm, plump, and youthful skin with anti-glycation actives. Glycation is a unique phenomenon where excess sugar molecules from your diet bind to essential proteins like collagen and elastin. This binding process can affect the structural proteins in your skin, like collagen and elastin, which are crucial for maintaining its firmness and elasticity. This results in wrinkles, loss of elasticity, and can even trigger excess pigment production, leading to dark marks and dullness.

Prevent and reverse the effects of glycation by adopting a low-sugar diet and incorporating targeted skincare with anti-glycation actives. These specialised ingredients help prevent sugar from binding to your skin's proteins and repair existing damage, preserving your skin's health and radiance.

Anti-Wrinkle

Anti-wrinkle skincare is focused on both preventing and visibly reducing the formation of lines by targeting the structural and dynamic causes of wrinkles within the skin. Fine lines and deeper wrinkles develop as collagen and elastin decline, cell turnover slows and repeated facial movements create creases that become etched over time. Advanced formulations address these mechanisms through a combination of elastin-stimulating actives, smoothing peptides that help relax the appearance of expression lines, and deeply hydrating ingredients that plump the skin from within. By reinforcing the skin’s architecture while softening surface contractions and improving elasticity, anti-wrinkle skincare delivers a visibly smoother complexion.

Regenerating

Regenerating skincare actively stimulates the formation of new, healthier skin, working in alignment with the skin’s innate renewal processes. Central to this are growth factors—effectively encouraging the development of new skin tissue. Peptides complement this by acting as targeted messengers guiding the skin to rebuild with greater strength and structural integrity. Stem cell–derived actives further support this environment by delivering protective and regenerative signals that optimize cellular function and renewal. While these mechanisms are synonymous with advanced anti-ageing—improving firmness, elasticity and overall skin quality—they are equally valuable in addressing scarring, as they promote tissue repair, accelerate regeneration and help restore a smoother, more even skin surface.

Skin Barrier Strengthening

Strengthening your skin barrier involves replenishing the key elements in the top layer of your skin (stratum corneum), leading to a stronger and healthier barrier. These essential elements include lipids (ceramides, fatty acids, and cholesterol) and Natural Moisturizing Factors (amino acids, hyaluronic acid, etc.). Various factors, such as incorrect skincare use, seasonal changes, and aesthetic treatments, can damage your skin barrier. When this happens, your skin loses excess water through Trans Epidermal Water Loss (T.E.W.L) and becomes less capable of defending against environmental stressors, resulting in dryness, sensitivity, and irritation.

A healthy skin barrier is crucial for overall skin health as it helps prevent hydration loss, protects against environmental damage, and reduces the risk of skin conditions like eczema and acne. By strengthening your skin barrier, you ensure your skin remains well-hydrated, resilient, and protected.

Firming & Lifting

Firming & Lifting skincare is designed to restore strength, structure, and definition to the skin, creating a visibly tighter, more sculpted appearance. As the skin loses collagen and elasticity over time, it can begin to soften and sag, losing its natural contours. Advanced formulations work to rebuild this support from within—boosting firmness while helping to visibly lift and redefine the skin. The result is a smoother, more toned complexion with enhanced bounce and resilience, where facial contours appear sharper and elevated.

Plumping

Plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

Anti-Pigmentation

Dealing with pigmentation means targeting melanin overproduction to reduce dark spots and prevent new ones. Melanin production can be triggered by UV exposure, pollution, hormonal changes (like during pregnancy), and inflammation (from acne or cuts). This excess pigment is then transferred to surrounding cells in epidermis called keratinocytes, which then moves to the skin's surface, causing visible dark spots.

To treat hyperpigmentation, a personalised and consistent approach is needed. Our anti-pigmentation products include lightening agents to block tyrosinase (the enzyme that creates melanin), antioxidants to fight free radicals, and ingredients to speed up skin cell turnover, removing pigmented cells. Using broad-spectrum sun protection is crucial to prevent new pigmentation during treatment.

Scar-Repairing

Anti-Scarring skincare targets the textured scars left by acne breakouts. These scars form due to inflammation disrupting collagen and elastin fibres leading to uneven healing and indented areas. Anti-Scarring actives harness growth factors and exfoliating actives to stimulate cell repair and regeneration, optimising the skin's healing process to reduce scar formation. They also effectively diminish older scars, improving overall skin texture and leaving you with a smoother complexion and significantly reduced scar visibility.

Brightening (Energising)

Brightening skincare involves using active ingredients to boost your blood circulation, detoxification and cellular energy. Improved blood circulation brings more essential nutrients and oxygen to your skin, while detoxification helps eliminate cell waste and impurities that can make your skin look dull. Certain active ingredients also enhance your skin's metabolism and regeneration. These combined actions restore your skin's vitality and radiant appearance, giving you a fresh, energised complexion.

Prevents Collagen Breakdown

By preventing collagen breakdown (Collagenase), you preserve your skin's firmness and elasticity. Inhibiting the enzymes that degrade collagen helps maintain the skin's structural integrity, reducing the appearance of fine lines and wrinkles. This promotes a firmer, more lifted complexion. The result is resilient, plump skin that defies the signs of ageing, keeping you looking youthful and radiant.

  • - + Anti-Ageing (Glycation)
  • - + Anti-Wrinkle
  • - + Regenerating
  • - + Skin Barrier Strengthening
  • - + Firming & Lifting
  • - + Plumping
  • - + Anti-Pigmentation
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Prevents Collagen Breakdown

Active Ingredients

  • - + Carcinine
  • - + Mimosa Extract
Carcinine

Glycation is a natural biological process in which sugars bind to proteins such as collagen and elastin, forming harmful molecules known as Advanced Glycation End Products (AGEs). Over time, these AGEs accumulate and cause the skin’s support structure to stiffen and weaken, leading to wrinkles, dullness, and loss of elasticity. Preventing or reducing glycation is therefore essential to maintaining smooth, firm, and resilient skin.

Carcinine is a synthetic peptide, rich in antioxidant and anti-glycation properties, it works by binding to sugars before they attach to proteins, effectively inhibiting AGE formation. It can also help neutralise existing AGEs, reducing their impact on collagen and elastin integrity. In addition, Carcinine’s antioxidant activity helps to protect skin cells from oxidative stress and support the natural repair of structural proteins. It's beneficial for mature skin to help maintain firmness, elasticity, and brightness; as it protects collagen and elastin from glycation damage and promotes their repair.

Mimosa Extract

Mimosa Extract has the ability to protect and repair collagen and elastin fibres structures which have been damaged by glycation. The reason this is so important is because collagen and elastin is what keeps skin youthful, smooth, plump and taught. Preserving these fibres is a necessary step in anti-ageing.

  • - + Carcinine
  • - + Mimosa Extract
Glycation Phenomenon

Glycation is a lesser-known yet impactful process in skincare, where excess sugar molecules in the body bind to essential proteins like collagen and elastin. This binding forms advanced glycation end-products (AGEs), which can take a toll on our skin’s appearance and vitality. Glycation weakens collagen and elastin, the proteins responsible for keeping our skin firm, elastic, and youthful. Over time, this process contributes to the loss of skin elasticity, the formation of wrinkles, sagging, and a dull, uneven skin tone, making the skin look older and less vibrant. When sugars attach to proteins, they create AGEs, which damage the skin’s structural fibres, leading to visible signs of ageing. Glycation doesn’t just impact the surface; it compromises the very foundation of the skin’s firmness and radiance. To combat this, incorporating antioxidants and anti-inflammatory ingredients into your skincare routine is key. These powerful ingredients help neutralise free radicals and protect the skin’s structure, preserving elasticity and minimising the visible effects of glycation. With the right anti-glycation skincare, you’ll notice your skin feels firmer, looks more even, and retains a healthy glow. By consistently using products rich in antioxidants and soothing anti-inflammatory ingredients, you can help preserve your skin’s youthful structure and protect it from premature ageing. Addressing glycation in your skincare routine means taking proactive steps to protect your skin from one of the hidden causes of ageing. By nurturing your skin with targeted ingredients that defend against glycation, you’ll enjoy a smoother, firmer complexion that looks and feels revitalised. Embrace the power of anti-glycation skincare and keep your skin looking youthful, bright, and beautifully resilient.

Clinical Proofs

EFFICACY TEST :
The test revealed a gain of 2 years of glycation in just 2 months of use (efficacy tests)
*Following a usage test carried out on 22 volunteers who applied the product twice daily for 2 months.
TEST ON SKIN EXPLANTS
We tested the Sérum A-Glyca on skin explants and observe its protective power on fibrillin-1.
Fibrillin-1 is a glycoprotein and an essential component of elastic network of the dermis. It is typically
used as a biomarker of the structural state of the extracellular matrix of the dermis.
Variation vs T (Témoin) or MG (
glycative agent)
Aminoguanidine (antiglycation
reference on the market)
Sérum A-Glyca
Fribrilline-1 T
MG
Aminoguanidine is an anti-glycation reference. The test showed that in the presence of a glycan
agent (MG = Methylglyoxal) Sérum A-Glyca better protects fibrillin of glycation than the anti-glycation
reference.
Sérum A-Glyca has good anti-glycation activity by inhibiting completely the alteration of the
fibrillin

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Spotlight

Glycation Phenomenon

Glycation is a lesser-known yet impactful process in skincare, where excess sugar molecules in the body bind to essential proteins like collagen and elastin. This binding forms advanced glycation end-products (AGEs), which can take a toll on our skin’s appearance and vitality. Glycation weakens collagen and elastin, the proteins responsible for keeping our skin firm, elastic, and youthful. Over time, this process contributes to the loss of skin elasticity, the formation of wrinkles, sagging, and a dull, uneven skin tone, making the skin look older and less vibrant. When sugars attach to proteins, they create AGEs, which damage the skin’s structural fibres, leading to visible signs of ageing. Glycation doesn’t just impact the surface; it compromises the very foundation of the skin’s firmness and radiance. To combat this, incorporating antioxidants and anti-inflammatory ingredients into your skincare routine is key. These powerful ingredients help neutralise free radicals and protect the skin’s structure, preserving elasticity and minimising the visible effects of glycation. With the right anti-glycation skincare, you’ll notice your skin feels firmer, looks more even, and retains a healthy glow. By consistently using products rich in antioxidants and soothing anti-inflammatory ingredients, you can help preserve your skin’s youthful structure and protect it from premature ageing. Addressing glycation in your skincare routine means taking proactive steps to protect your skin from one of the hidden causes of ageing. By nurturing your skin with targeted ingredients that defend against glycation, you’ll enjoy a smoother, firmer complexion that looks and feels revitalised. Embrace the power of anti-glycation skincare and keep your skin looking youthful, bright, and beautifully resilient.

Clinical Proofs

Clinical Proofs

EFFICACY TEST :
The test revealed a gain of 2 years of glycation in just 2 months of use (efficacy tests)
*Following a usage test carried out on 22 volunteers who applied the product twice daily for 2 months.
TEST ON SKIN EXPLANTS
We tested the Sérum A-Glyca on skin explants and observe its protective power on fibrillin-1.
Fibrillin-1 is a glycoprotein and an essential component of elastic network of the dermis. It is typically
used as a biomarker of the structural state of the extracellular matrix of the dermis.
Variation vs T (Témoin) or MG (
glycative agent)
Aminoguanidine (antiglycation
reference on the market)
Sérum A-Glyca
Fribrilline-1 T
MG
Aminoguanidine is an anti-glycation reference. The test showed that in the presence of a glycan
agent (MG = Methylglyoxal) Sérum A-Glyca better protects fibrillin of glycation than the anti-glycation
reference.
Sérum A-Glyca has good anti-glycation activity by inhibiting completely the alteration of the
fibrillin

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Why I love it

  • "The efficacy of Biologique Recherche relies not only on its science-driven approach to balancing and curing the skin, but on its prescriptive and tailored nature."

    X Natalie K-F

    Founder, Embassy of Beauty

  • Biologique Recherche Serum A-Glyca 30ml
    Biologique Recherche

    Serum A-Glyca

    £200

    Biologique Recherche Serum A-Glyca combats ageing caused by glycation, preventing sugar from binding to collagen and elastin and protecting deep skin cells. It reduces deep lines and wrinkles, firms the skin and boosts radiance.

    Mimosa Extract protects and repairs collagen and elastin fibres damaged by glycation, preserving the structural proteins that keep skin youthful, smooth, plump and taut. It progressively restores the integrity of the dermal matrix, improving firmness, elasticity and the skin's overall youthful appearance.

    Carcinine is a powerful antioxidant dipeptide that scavenges advanced glycation end-products (AGEs) and protects cellular proteins from further glycation-related damage. Together, these two actives work to undo the yellowing, stiffening and loss of bounce associated with glycated skin, delivering a visibly firmer, brighter and more resilient complexion with continued use.

    View product