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Creme PTO Metamorphique

(5)
PLUMP & LIFT ELIXIR
Creme PTO Metamorphique
Biologique Recherche
(5)
Benefits
  • Regenerating
  • Anti-Wrinkle
  • Barrier-Strengthening
  • Firming
  • Lifting
  • Plumping
  • Anti-Pigmentation
  • Scar-Repairing
  • Brightening
  • Hydrating
  • Antioxidant
  • Cellular Anti-Ageing

The Biologique Recherche Creme PTO Metamorphique is an advanced lifting, volumising and redensifying cream for skin showing signs of sagging, volume loss and loss of facial contour. Formulated around a powerful complex of stem cell-stimulating botanicals and structural support actives, it restructures the facial oval and visibly restores firmness and definition.

Goji Berry Extract stimulates skin stem cells to produce exosomes — the cell-to-cell communication messengers that trigger collagen and elastin synthesis — reducing wrinkles and sagging for a visibly younger complexion.

Cassava Extract forms a viscoelastic film on the skin, creating an immediate tightening and lifting effect, while Plantain Seed Extract strengthens the collagen network, enhances elastin fibre quality and stimulates natural Hyaluronic Acid production to restore volume and density.

Shrubby Everlasting Extract boosts periostin production to improve collagen quality and increase skin density for a more toned and lifted appearance. Smithsonite Extract — naturally rich in zinc — stimulates DNA defence mechanisms and provides anti-glycation and photo-protective properties.

Marine Exopolysaccharide stimulates collagen and elastin synthesis and delivers an immediate, durable lifting effect on the collagen fibre network. Peony Extract preserves adipocyte integrity in the deeper skin layers to prevent volume loss, and Baobab Extract stimulates fibroblast activity and reinforces the skin's structural matrix — delivering clinically proven improvements in firmness (+23%) and elasticity (+20%) after 56 days.

Read more

The Biologique Recherche Creme PTO Metamorphique is an advanced lifting, volumising and redensifying cream for skin showing signs of sagging, volume loss and loss of facial contour. Formulated around a powerful complex of stem cell-stimulating botanicals and structural support actives, it restructures the facial oval and visibly restores firmness and definition.

Goji Berry Extract stimulates skin stem cells to produce exosomes — the cell-to-cell communication messengers that trigger collagen and elastin synthesis — reducing wrinkles and sagging for a visibly younger complexion.

Cassava Extract forms a viscoelastic film on the skin, creating an immediate tightening and lifting effect, while Plantain Seed Extract strengthens the collagen network, enhances elastin fibre quality and stimulates natural Hyaluronic Acid production to restore volume and density.

Shrubby Everlasting Extract boosts periostin production to improve collagen quality and increase skin density for a more toned and lifted appearance. Smithsonite Extract — naturally rich in zinc — stimulates DNA defence mechanisms and provides anti-glycation and photo-protective properties.

Marine Exopolysaccharide stimulates collagen and elastin synthesis and delivers an immediate, durable lifting effect on the collagen fibre network. Peony Extract preserves adipocyte integrity in the deeper skin layers to prevent volume loss, and Baobab Extract stimulates fibroblast activity and reinforces the skin's structural matrix — delivering clinically proven improvements in firmness (+23%) and elasticity (+20%) after 56 days.

Read less

50 ml

£232
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Get The Set
Biologique Recherche Fine Line & Volume Restore Collection
Fine Line & Volume Restore Collection

Creme PTO Metamorphique
Creme Biofixine

£555 £527

More Info

  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
Who it is for
Green tick
For you if

Loss of Tone

Loss of Firmness

Wrinkles

Volume Loss

How to Apply
Apply a hazelnut-sized amount of Crème PTO Metamorphique over the face, neck and décolleté. Massage delicately with fingertips, working with upward and outward strokes until the product is fully absorbed.
Ingredients

Scroll down the page for a full breakdown of the active ingredients.

Water (Aqua), Coco-Caprylate/Caprate, Caprylic/Capric Triglyceride, C10-18 Triglycerides, Smithsonite Extract, Glycerin, C12-16 Alcohols, Methylpropanediol, Hydrogenated Lecithin, Palmitic Acid, Cetyl Alcohol, Glyceryl Stearate Citrate, Tapioca Starch, Secale Cereale (Rye) Seed Extract, Paeonia Albiflora Root Extract, Helichrysum Stoechas Extract, Helianthus Annuus (Sunflower) Seed Oil, Plantago Lanceolata Seed Extract, Lycium Barbarum Callus Culture Extract, Alteromonas Ferment Extract, Diaminopropionoyl Tripeptide-33, Maltodextrin, Tocopherol, Lecithin, Isomalt, 1,2-Hexanediol, Sorbitan Isostearate, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Polysorbate 60, Caprylyl Glycol, Phenylpropanol, Phenethyl Alcohol


Please note: The ingredients listed in this product are subject to change as the formulation is updated. We aim to update the INCI list as soon as possible, but we encourage you to read the ingredient list on the product itself to ensure it's suitable for your personal use.

Smell & Texture

Smell: It has a clean, subtle, slightly botanical scent

Texture: A medium-thick, creamy and smooth texture

About the Brand
Brand logo
Founded in Paris in the late 1970s by biologist Yvan Allouche and physiotherapist Josette Allouche, Biologique Recherche began as a laboratory for bespoke, high-performance formulas for elite skin professionals. Their medical-grade precision and artisanal formulation, paired with consummate savoir-faire, underpin their reputation for outstanding, clinically proven results.

Biologique Recherche treats skin according to its Skin Instant©, the skin’s precise, evolving state. Each formula is loaded with active ingredients in exceptional concentrations, then prescribed to address those real-time needs. This precision approach corrects imbalances, restores function, and delivers visible, lasting transformation.

Cold-processed actives are the core of Biologique Recherche. Formulated at 18–25°C, this method avoids the 70°C heat of standard processing that breaks down actives. Botanical, marine, and biotechnological extracts stay intact for higher absorption, stronger repair, and better tolerance. Antioxidants, peptides, and enzymes remain stable, ensuring consistent, visible results.

The Benefits

  • - + Regenerating
  • - + Anti-Wrinkle
  • - + Skin Barrier Strengthening
  • - + Firming & Lifting
  • - + Plumping
  • - + Anti-Pigmentation
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Hydrating
  • - + Photo-Protecting
  • - + Anti-Ageing (Glycation)
  • - + Antioxidant
Regenerating

Regenerating skincare actively stimulates the formation of new, healthier skin, working in alignment with the skin’s innate renewal processes. Central to this are growth factors—effectively encouraging the development of new skin tissue. Peptides complement this by acting as targeted messengers guiding the skin to rebuild with greater strength and structural integrity. Stem cell–derived actives further support this environment by delivering protective and regenerative signals that optimize cellular function and renewal. While these mechanisms are synonymous with advanced anti-ageing—improving firmness, elasticity and overall skin quality—they are equally valuable in addressing scarring, as they promote tissue repair, accelerate regeneration and help restore a smoother, more even skin surface.

Anti-Wrinkle

Anti-wrinkle skincare is focused on both preventing and visibly reducing the formation of lines by targeting the structural and dynamic causes of wrinkles within the skin. Fine lines and deeper wrinkles develop as collagen and elastin decline, cell turnover slows and repeated facial movements create creases that become etched over time. Advanced formulations address these mechanisms through a combination of elastin-stimulating actives, smoothing peptides that help relax the appearance of expression lines, and deeply hydrating ingredients that plump the skin from within. By reinforcing the skin’s architecture while softening surface contractions and improving elasticity, anti-wrinkle skincare delivers a visibly smoother complexion.

Skin Barrier Strengthening

Strengthening your skin barrier involves replenishing the key elements in the top layer of your skin (stratum corneum), leading to a stronger and healthier barrier. These essential elements include lipids (ceramides, fatty acids, and cholesterol) and Natural Moisturizing Factors (amino acids, hyaluronic acid, etc.). Various factors, such as incorrect skincare use, seasonal changes, and aesthetic treatments, can damage your skin barrier. When this happens, your skin loses excess water through Trans Epidermal Water Loss (T.E.W.L) and becomes less capable of defending against environmental stressors, resulting in dryness, sensitivity, and irritation.

A healthy skin barrier is crucial for overall skin health as it helps prevent hydration loss, protects against environmental damage, and reduces the risk of skin conditions like eczema and acne. By strengthening your skin barrier, you ensure your skin remains well-hydrated, resilient, and protected.

Firming & Lifting

Firming & Lifting skincare is designed to restore strength, structure, and definition to the skin, creating a visibly tighter, more sculpted appearance. As the skin loses collagen and elasticity over time, it can begin to soften and sag, losing its natural contours. Advanced formulations work to rebuild this support from within—boosting firmness while helping to visibly lift and redefine the skin. The result is a smoother, more toned complexion with enhanced bounce and resilience, where facial contours appear sharper and elevated.

Plumping

Plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

Anti-Pigmentation

Dealing with pigmentation means targeting melanin overproduction to reduce dark spots and prevent new ones. Melanin production can be triggered by UV exposure, pollution, hormonal changes (like during pregnancy), and inflammation (from acne or cuts). This excess pigment is then transferred to surrounding cells in epidermis called keratinocytes, which then moves to the skin's surface, causing visible dark spots.

To treat hyperpigmentation, a personalised and consistent approach is needed. Our anti-pigmentation products include lightening agents to block tyrosinase (the enzyme that creates melanin), antioxidants to fight free radicals, and ingredients to speed up skin cell turnover, removing pigmented cells. Using broad-spectrum sun protection is crucial to prevent new pigmentation during treatment.

Scar-Repairing

Anti-Scarring skincare targets the textured scars left by acne breakouts. These scars form due to inflammation disrupting collagen and elastin fibres leading to uneven healing and indented areas. Anti-Scarring actives harness growth factors and exfoliating actives to stimulate cell repair and regeneration, optimising the skin's healing process to reduce scar formation. They also effectively diminish older scars, improving overall skin texture and leaving you with a smoother complexion and significantly reduced scar visibility.

Brightening (Energising)

Brightening skincare involves using active ingredients to boost your blood circulation, detoxification and cellular energy. Improved blood circulation brings more essential nutrients and oxygen to your skin, while detoxification helps eliminate cell waste and impurities that can make your skin look dull. Certain active ingredients also enhance your skin's metabolism and regeneration. These combined actions restore your skin's vitality and radiant appearance, giving you a fresh, energised complexion.

Hydrating

Hydration is a fundamental part of healthy skincare, focusing on maintaining and restoring the skin’s water content. Well-hydrated skin appears plump, smooth and radiant, while dehydration can lead to dullness, tightness, fine lines and increased sensitivity.
Hydrating the skin can work through a fascinating mix of ingredients with different roles. Humectants like hyaluronic acid and glycerin act like water magnets, pulling water into the skin to instantly plump and smooth, while Natural Moisturizing Factors (NMFs)—such as urea, amino acids and sodium PCA—mimic the skin’s own hydration system, helping it hold onto water and stay balanced from within.
Adding humectants like hyaluronic acid to your routine will restore your skin's healthy glow, minimize fine lines, and provide a plumping effect.

Photo-Protecting

Photo-protecting skincare at a cellular level focuses on defending the skin against the internal damage triggered by UV exposure, rather than simply blocking rays at the surface. Ultraviolet radiation generates free radicals and disrupts cellular DNA, accelerating collagen breakdown, inflammation, and premature ageing. Advanced formulations work by neutralising oxidative stress, supporting DNA repair mechanisms, and strengthening the skin’s natural defence systems to limit long-term damage. By preserving cellular integrity and maintaining healthy skin function, this approach helps prevent visible signs of photo-ageing—such as wrinkles, loss of firmness, and uneven tone.

Anti-Ageing (Glycation)

Combat Glycation and maintain firm, plump, and youthful skin with anti-glycation actives. Glycation is a unique phenomenon where excess sugar molecules from your diet bind to essential proteins like collagen and elastin. This binding process can affect the structural proteins in your skin, like collagen and elastin, which are crucial for maintaining its firmness and elasticity. This results in wrinkles, loss of elasticity, and can even trigger excess pigment production, leading to dark marks and dullness.

Prevent and reverse the effects of glycation by adopting a low-sugar diet and incorporating targeted skincare with anti-glycation actives. These specialised ingredients help prevent sugar from binding to your skin's proteins and repair existing damage, preserving your skin's health and radiance.

Antioxidant

Antioxidant skincare is dedicated to protecting the skin against oxidative stress—one of the primary drivers of premature ageing and cellular damage—while preserving overall skin integrity and vitality. These formulations rely on potent molecules such as vitamin C, vitamin E, and polyphenols, which neutralize free radicals generated by UV exposure and environmental aggressors before they can compromise cellular structures like lipids, proteins, and DNA. Beyond defence, many antioxidants also support repair processes and enhance collagen stability, contributing to improved firmness, brightness and resilience. The result is skin that is not only shielded from ongoing damage but maintained in a healthier, more luminous state over time.

  • - + Regenerating
  • - + Anti-Wrinkle
  • - + Skin Barrier Strengthening
  • - + Firming & Lifting
  • - + Plumping
  • - + Anti-Pigmentation
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Hydrating
  • - + Photo-Protecting
  • - + Anti-Ageing (Glycation)
  • - + Antioxidant

Active Ingredients

  • - + Goji Berry Extract
  • - + Cassava Extract
  • - + Plantain Seed Extract
  • - + Shrubby Everlasting Extract
  • - + Smithsonite Extract
  • - + Marine Exopolysaccharide
  • - + Peony Extract
  • - + Baobab Extract
Goji Berry Extract

Goji Berry Extract has exceptional anti-ageing and regenerating properties. It stimulates stem cells to produce exosomes. Exosomes are involved in cell-to-cell communication, triggering rejuvenation cycles and stimulating the synthesis of Collagen and Elastin, which keep the skin plump and smooth. This results in a reduction in wrinkles and sagging, for an overall younger complexion.

Cassava Extract

Cassava Extract, forms a flexible, viscoelastic film on the skin. This creates a tightening effect, visibly lifting and defining facial contours.

Plantain Seed Extract

Plantain has a unique ability to strengthen the Collagen network in the dermis, providing internal support and density to the skin. Additionally, Plantain Seed Extract enhances the quality of the Elastin Fibers, contributing to the skin's firmness and ability to maintain toned facial contours. Finally, it stimulates the natural production of Hyaluronic Acid, which plumps the skin and restores youthful volume.

Shrubby Everlasting Extract

Shrubby Everlasting extract boosts the production of periostin, a protein that helps regenerate skin. This improves collagen quality and increases skin density. With regular use, it firms and tones the skin, defining facial contours for a more toned and lifted appearance.

Smithsonite Extract

Smithsonite Extract is a mineral extract from smithsonite stone. Naturally rich in zinc, it stimulates a key protein involved in DNA defence mechanisms. The extract also has photo-protective and anti-glycation properties working to prevent early collagen and elastin breakdown, maintaining skin's firmness and youthfulness.

Marine Exopolysaccharide

The Marine Exopolysaccharide stimulates collagen and elastin synthesis to improve the skin's firmness, smoothness and plumpness. Furthermore, it also has a tightening benefit on the collagen fibre network, which provides an immediate and durable lifting effect, filling in fine lines and wrinkles.

Peony Extract

Peony Extract works to prevent skin ageing by enhancing skin cell communication. It specifically works on deeper layers of the skin to prevent early adipocyte (fat cells) loss and migration, preserving facial volume, density and facial contours.

Baobab Extract

Baobab Extract is rich in vitamin C, B vitamins B3 & B6, amino acids, and polysaccharides. It stimulates fibroblast activity to increase collagen I and elastin production, reinforcing the skin’s structural support. Its polysaccharides form a hydrating, plumping film that enhances elasticity and suppleness, while antioxidants like vitamin C and polyphenols defend against oxidative damage and slow collagen breakdown. Together, these effects help firm, smooth, and lift the skin over time.

  • - + Goji Berry Extract
  • - + Cassava Extract
  • - + Plantain Seed Extract
  • - + Shrubby Everlasting Extract
  • - + Smithsonite Extract
  • - + Marine Exopolysaccharide
  • - + Peony Extract
  • - + Baobab Extract
Cassava Extract

Cassava extract, derived from the root of Manihot esculenta, is a skincare ingredient offering benefits for hydration, anti-aging, skin brightening, and environmental protection. Its hydrating and soothing properties help maintain skin moisture, while its antioxidant content, including vitamin C, combats free radicals that contribute to premature aging. Vitamin C also supports collagen synthesis, enhancing skin firmness and elasticity. Additionally, cassava extract inhibits inflammatory mediators, alleviating skin irritation, and acts as a protective barrier against environmental stressors. The presence of copper further aids in cellular energy production and repair processes, promoting overall skin health.

Clinical Proofs

EFFICACY TEST:
Test conducted on 20 women aged 45 to 71. Clinical scoring was performed at the beginning of the study, after 28
days, and after using the product twice daily for 56 days.
- Facial ptosis: significant decrease in the observable criteria (below), which standardises facial
volume.
AFTER 28 DAYS
% difference
AFTER 56 DAYS
% difference
Degree of facial ptosis -6% -13%
Degree of jaw folds -9% -21%
Degree of wrinkles induced by lower part of facial
ptosis -8% -18%
Degree of wrinkle visibility related to facial ptosis -6% -20%
Measurements were also taken after using the product twice a day for 56 days.
- The skin’s elasticity is improved by +20%
- The skin’s firmness is improved by +23%

USAGE TEST:
Test conducted on 20 women aged 45 to 71 after using the product twice a day for 56 days.

- 90% of women said their skin was tightened
- 90% of women said the product had a lifting effect
- 85% of women said the oval of the face was restructured and redefined
- 95% of women said their facial volume was rebalanced
- 90% of women said their skin was plumper
- 95% of women said wrinkles and fine lines were smoothed
- 95% of women said their skin was protected

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Spotlight

Cassava Extract

Cassava extract, derived from the root of Manihot esculenta, is a skincare ingredient offering benefits for hydration, anti-aging, skin brightening, and environmental protection. Its hydrating and soothing properties help maintain skin moisture, while its antioxidant content, including vitamin C, combats free radicals that contribute to premature aging. Vitamin C also supports collagen synthesis, enhancing skin firmness and elasticity. Additionally, cassava extract inhibits inflammatory mediators, alleviating skin irritation, and acts as a protective barrier against environmental stressors. The presence of copper further aids in cellular energy production and repair processes, promoting overall skin health.

Clinical Proofs

Clinical Proofs

EFFICACY TEST:
Test conducted on 20 women aged 45 to 71. Clinical scoring was performed at the beginning of the study, after 28
days, and after using the product twice daily for 56 days.
- Facial ptosis: significant decrease in the observable criteria (below), which standardises facial
volume.
AFTER 28 DAYS
% difference
AFTER 56 DAYS
% difference
Degree of facial ptosis -6% -13%
Degree of jaw folds -9% -21%
Degree of wrinkles induced by lower part of facial
ptosis -8% -18%
Degree of wrinkle visibility related to facial ptosis -6% -20%
Measurements were also taken after using the product twice a day for 56 days.
- The skin’s elasticity is improved by +20%
- The skin’s firmness is improved by +23%

USAGE TEST:
Test conducted on 20 women aged 45 to 71 after using the product twice a day for 56 days.

- 90% of women said their skin was tightened
- 90% of women said the product had a lifting effect
- 85% of women said the oval of the face was restructured and redefined
- 95% of women said their facial volume was rebalanced
- 90% of women said their skin was plumper
- 95% of women said wrinkles and fine lines were smoothed
- 95% of women said their skin was protected

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Why I love it

  • "The efficacy of Biologique Recherche relies not only on its science-driven approach to balancing and curing the skin, but on its prescriptive and tailored nature."

    X Natalie K-F

    Founder, Embassy of Beauty

  • Biologique Recherche Creme PTO Metamorphique 50ml
    Biologique Recherche

    Creme PTO Metamorphique

    £232

    The Biologique Recherche Creme PTO Metamorphique is an advanced lifting, volumising and redensifying cream for skin showing signs of sagging, volume loss and loss of facial contour. Formulated around a powerful complex of stem cell-stimulating botanicals and structural support actives, it restructures the facial oval and visibly restores firmness and definition.

    Goji Berry Extract stimulates skin stem cells to produce exosomes — the cell-to-cell communication messengers that trigger collagen and elastin synthesis — reducing wrinkles and sagging for a visibly younger complexion.

    Cassava Extract forms a viscoelastic film on the skin, creating an immediate tightening and lifting effect, while Plantain Seed Extract strengthens the collagen network, enhances elastin fibre quality and stimulates natural Hyaluronic Acid production to restore volume and density.

    Shrubby Everlasting Extract boosts periostin production to improve collagen quality and increase skin density for a more toned and lifted appearance. Smithsonite Extract — naturally rich in zinc — stimulates DNA defence mechanisms and provides anti-glycation and photo-protective properties.

    Marine Exopolysaccharide stimulates collagen and elastin synthesis and delivers an immediate, durable lifting effect on the collagen fibre network. Peony Extract preserves adipocyte integrity in the deeper skin layers to prevent volume loss, and Baobab Extract stimulates fibroblast activity and reinforces the skin's structural matrix — delivering clinically proven improvements in firmness (+23%) and elasticity (+20%) after 56 days.

    View product