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Creme Dermo-RL

(4)
DEEP NOURISHMENT
Creme Dermo-RL
Biologique Recherche
(4)
Benefits
  • Nourishing
  • Barrier-Strengthening
  • Anti-Wrinkle
  • Plumping
  • Regenerating
  • Firming
  • Lifting
  • Anti-Pigmentation
  • Scar-Repairing
  • Brightening
  • Antioxidant
  • Hydrating

Biologique Recherche Creme Dermo-RL is a luxurious, rich cream that deeply nourishes and comforts very dry skin. It provides protection for those exposed to harsh weather and cold climates.

Shea Butter provides the richest lipid nourishment in the formula, delivering a dense complex of fatty acids and phytosterols that deeply condition the skin, repair the barrier and relieve dryness and tightness.

The Glycoprotein of the Antarctic Microorganisms prevents skin from drying, boosts collagen and elastin production and helps keep the skin smooth and resilient under environmental stress.

A Complex made from Prickly Pear Cactus Extract and Jojoba Oil enhances cellular protection against environmental stressors including sun exposure, temperature changes and pollution, while improving the skin's capacity to retain moisture.

Cranberry Seed Oil, Walnut Extract, the Complex of Hyaluronic Acid & Rhizobium and Cotton Oil complete the formula, delivering comprehensive hydration, antioxidant protection and barrier repair for a complexion that is visibly richer, more comfortable and lastingly moisturised.

Read more

Biologique Recherche Creme Dermo-RL is a luxurious, rich cream that deeply nourishes and comforts very dry skin. It provides protection for those exposed to harsh weather and cold climates.

Shea Butter provides the richest lipid nourishment in the formula, delivering a dense complex of fatty acids and phytosterols that deeply condition the skin, repair the barrier and relieve dryness and tightness.

The Glycoprotein of the Antarctic Microorganisms prevents skin from drying, boosts collagen and elastin production and helps keep the skin smooth and resilient under environmental stress.

A Complex made from Prickly Pear Cactus Extract and Jojoba Oil enhances cellular protection against environmental stressors including sun exposure, temperature changes and pollution, while improving the skin's capacity to retain moisture.

Cranberry Seed Oil, Walnut Extract, the Complex of Hyaluronic Acid & Rhizobium and Cotton Oil complete the formula, delivering comprehensive hydration, antioxidant protection and barrier repair for a complexion that is visibly richer, more comfortable and lastingly moisturised.

Read less

50 ml

£222
MyEB
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(£75)
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(£150)
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(£200)
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More Info

  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
  • - + Who it is for
  • - + How to Apply
  • - + Ingredients
  • - + Smell & Texture
  • - + About the Brand
Who it is for
Green tick
For you if

Dry Skin

Reactive Skin

Prefer Buttery Textures

Sensitive Skin

How to Apply
Apply a hazelnut-sized amount of Crème Dermo-RL over the face, neck and décolleté. Massage delicately with fingertips, working with upward and outward strokes until the product is fully absorbed.
Ingredients

Scroll down the page for a full breakdown of the active ingredients.

Water (Aqua), Vitis Vinifera (Grape) Seed Oil, Butyrospermum Parkii (Shea) Butter, Propanediol Dicaprylate, C12-16 Alcohols, Gossypium Herbaceum (Cotton) Seed Oil, Pentylene Glycol, Pentaerythrityl Tetraestearate, Polyamide-5, Vaccinium Macrocarpon (Cranberry) Seed Oil, Xylitylglucosides, Hydrogenated Lecithin, Palmitic Acid, Glycerin, Simmondsia Chinensis (Jojoba) Seed Oil, Anhydroxylitol, Sodium Hyaluronate, Pseudoalteromonas Ferment Extract, Xylitol, Tocopherol, Helianthus Annuus (Sunflower) Seed Oil, Juglans Regia (Walnut) Seed Extract, Cananga Odorata Flower Oil, Citrus Aurantium Amara (Bitter Orange) Flower Oil, Opuntia Ficus-Indica Fruit Extract, Glyceryl Stearate Citrate, Polysorbate 60, Sorbitan Isostearate, Phenoxyethanol, Rhizobian Gum, Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer, Chlorphenesin, Salicylic Acid, Sodium Metabisulfite, Sodium Hydroxide, Benzyl Benzoate, Benzyl Salicylate, Farnesol, Geraniol, Limonene, Linalool.

* This product contains nut-derived ingredients and should be avoided by individuals with nut allergies.


Please note: The ingredients listed in this product are subject to change as the formulation is updated. We aim to update the INCI list as soon as possible, but we encourage you to read the ingredient list on the product itself to ensure it's suitable for your personal use.

Smell & Texture

Smell: It has a clean, subtle, slightly botanical scent

Texture: A thick, creamy and smooth texture

About the Brand
Brand logo
Founded in Paris in the late 1970s by biologist Yvan Allouche and physiotherapist Josette Allouche, Biologique Recherche began as a laboratory for bespoke, high-performance formulas for elite skin professionals. Their medical-grade precision and artisanal formulation, paired with consummate savoir-faire, underpin their reputation for outstanding, clinically proven results.

Biologique Recherche treats skin according to its Skin Instant©, the skin’s precise, evolving state. Each formula is loaded with active ingredients in exceptional concentrations, then prescribed to address those real-time needs. This precision approach corrects imbalances, restores function, and delivers visible, lasting transformation.

Cold-processed actives are the core of Biologique Recherche. Formulated at 18–25°C, this method avoids the 70°C heat of standard processing that breaks down actives. Botanical, marine, and biotechnological extracts stay intact for higher absorption, stronger repair, and better tolerance. Antioxidants, peptides, and enzymes remain stable, ensuring consistent, visible results.

The Benefits

  • - + Nourishing
  • - + Skin Barrier Strengthening
  • - + Reduces Trans Epidermal Water Loss
  • - + Anti-Wrinkle
  • - + Plumping
  • - + Regenerating
  • - + Firming & Lifting
  • - + Anti-Pigmentation
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Antioxidant
  • - + Photo-Protecting
  • - + Micro-Needling Effect
  • - + Hydrating
Nourishing

Nourishing skincare focuses on replenishing the skin with essential lipids, nutrients, and bioactive compounds to restore comfort, resilience, and optimal function. When the skin is depleted—whether through environmental stress, over-exfoliation, or natural ageing—it can become dry, fragile, and less able to protect itself. Nourishing formulations work to rebuild the lipid barrier using ingredients rich in fatty acids, vitamins, and antioxidants, helping to reinforce the skin’s structure while supporting repair and reducing moisture loss. By restoring what the skin lacks, this approach leaves it softer, stronger, and more supple.

Skin Barrier Strengthening

Strengthening your skin barrier involves replenishing the key elements in the top layer of your skin (stratum corneum), leading to a stronger and healthier barrier. These essential elements include lipids (ceramides, fatty acids, and cholesterol) and Natural Moisturizing Factors (amino acids, hyaluronic acid, etc.). Various factors, such as incorrect skincare use, seasonal changes, and aesthetic treatments, can damage your skin barrier. When this happens, your skin loses excess water through Trans Epidermal Water Loss (T.E.W.L) and becomes less capable of defending against environmental stressors, resulting in dryness, sensitivity, and irritation.

A healthy skin barrier is crucial for overall skin health as it helps prevent hydration loss, protects against environmental damage, and reduces the risk of skin conditions like eczema and acne. By strengthening your skin barrier, you ensure your skin remains well-hydrated, resilient, and protected.

Reduces Trans Epidermal Water Loss

Reducing Trans Epidermal Water Loss (TEWL) is key to maintaining your skin’s optimal hydration levels. By strengthening your skin’s natural barrier, these ingredients prevent water from escaping, keeping your skin well-hydrated and plump. The result is a smoother, more supple complexion with improved texture and resilience, giving you a healthier, more radiant look.

Anti-Wrinkle

Anti-wrinkle skincare is focused on both preventing and visibly reducing the formation of lines by targeting the structural and dynamic causes of wrinkles within the skin. Fine lines and deeper wrinkles develop as collagen and elastin decline, cell turnover slows and repeated facial movements create creases that become etched over time. Advanced formulations address these mechanisms through a combination of elastin-stimulating actives, smoothing peptides that help relax the appearance of expression lines, and deeply hydrating ingredients that plump the skin from within. By reinforcing the skin’s architecture while softening surface contractions and improving elasticity, anti-wrinkle skincare delivers a visibly smoother complexion.

Plumping

Plumping involves using active ingredients to boost the production of key structural components like collagen, the dermal-epidermal junction and glycosaminoglycans (GAGs), giving your skin more volume and density. Collagen provides structural support and firmness, while the dermal-epidermal junction, a thin connective layer, ensures smooth, wrinkle-free skin by facilitating cell communication. GAGs, like hyaluronic acid, keep your skin hydrated and plump from within. By stimulating these components, active ingredients help restore your skin's plumpness and radiance.

Regenerating

Regenerating skincare actively stimulates the formation of new, healthier skin, working in alignment with the skin’s innate renewal processes. Central to this are growth factors—effectively encouraging the development of new skin tissue. Peptides complement this by acting as targeted messengers guiding the skin to rebuild with greater strength and structural integrity. Stem cell–derived actives further support this environment by delivering protective and regenerative signals that optimize cellular function and renewal. While these mechanisms are synonymous with advanced anti-ageing—improving firmness, elasticity and overall skin quality—they are equally valuable in addressing scarring, as they promote tissue repair, accelerate regeneration and help restore a smoother, more even skin surface.

Firming & Lifting

Firming & Lifting skincare is designed to restore strength, structure, and definition to the skin, creating a visibly tighter, more sculpted appearance. As the skin loses collagen and elasticity over time, it can begin to soften and sag, losing its natural contours. Advanced formulations work to rebuild this support from within—boosting firmness while helping to visibly lift and redefine the skin. The result is a smoother, more toned complexion with enhanced bounce and resilience, where facial contours appear sharper and elevated.

Anti-Pigmentation

Dealing with pigmentation means targeting melanin overproduction to reduce dark spots and prevent new ones. Melanin production can be triggered by UV exposure, pollution, hormonal changes (like during pregnancy), and inflammation (from acne or cuts). This excess pigment is then transferred to surrounding cells in epidermis called keratinocytes, which then moves to the skin's surface, causing visible dark spots.

To treat hyperpigmentation, a personalised and consistent approach is needed. Our anti-pigmentation products include lightening agents to block tyrosinase (the enzyme that creates melanin), antioxidants to fight free radicals, and ingredients to speed up skin cell turnover, removing pigmented cells. Using broad-spectrum sun protection is crucial to prevent new pigmentation during treatment.

Scar-Repairing

Anti-Scarring skincare targets the textured scars left by acne breakouts. These scars form due to inflammation disrupting collagen and elastin fibres leading to uneven healing and indented areas. Anti-Scarring actives harness growth factors and exfoliating actives to stimulate cell repair and regeneration, optimising the skin's healing process to reduce scar formation. They also effectively diminish older scars, improving overall skin texture and leaving you with a smoother complexion and significantly reduced scar visibility.

Brightening (Energising)

Brightening skincare involves using active ingredients to boost your blood circulation, detoxification and cellular energy. Improved blood circulation brings more essential nutrients and oxygen to your skin, while detoxification helps eliminate cell waste and impurities that can make your skin look dull. Certain active ingredients also enhance your skin's metabolism and regeneration. These combined actions restore your skin's vitality and radiant appearance, giving you a fresh, energised complexion.

Antioxidant

Antioxidant skincare is dedicated to protecting the skin against oxidative stress—one of the primary drivers of premature ageing and cellular damage—while preserving overall skin integrity and vitality. These formulations rely on potent molecules such as vitamin C, vitamin E, and polyphenols, which neutralize free radicals generated by UV exposure and environmental aggressors before they can compromise cellular structures like lipids, proteins, and DNA. Beyond defence, many antioxidants also support repair processes and enhance collagen stability, contributing to improved firmness, brightness and resilience. The result is skin that is not only shielded from ongoing damage but maintained in a healthier, more luminous state over time.

Photo-Protecting

Photo-protecting skincare at a cellular level focuses on defending the skin against the internal damage triggered by UV exposure, rather than simply blocking rays at the surface. Ultraviolet radiation generates free radicals and disrupts cellular DNA, accelerating collagen breakdown, inflammation, and premature ageing. Advanced formulations work by neutralising oxidative stress, supporting DNA repair mechanisms, and strengthening the skin’s natural defence systems to limit long-term damage. By preserving cellular integrity and maintaining healthy skin function, this approach helps prevent visible signs of photo-ageing—such as wrinkles, loss of firmness, and uneven tone.

Micro-Needling Effect

Micro-needling effect skincare is designed to stimulate the regeneration of new, healthy skin by activating the skin’s natural repair mechanisms—without the need for needles. Through controlled micro-stimulation, these formulations encourage accelerated cell turnover and boost collagen and elastin production, resulting in firmer, smoother, and more youthful-looking skin. This regenerative process not only softens fine lines and improves skin density, but also helps reduce the appearance of pigmentation and scarring by promoting the renewal of more even, uniform skin. By continuously supporting the formation of fresh skin cells, this approach refines texture, enhances clarity, and reveals a complexion that appears more resilient, radiant, and visibly rejuvenated over time.

Hydrating

Hydration is a fundamental part of healthy skincare, focusing on maintaining and restoring the skin’s water content. Well-hydrated skin appears plump, smooth and radiant, while dehydration can lead to dullness, tightness, fine lines and increased sensitivity.
Hydrating the skin can work through a fascinating mix of ingredients with different roles. Humectants like hyaluronic acid and glycerin act like water magnets, pulling water into the skin to instantly plump and smooth, while Natural Moisturizing Factors (NMFs)—such as urea, amino acids and sodium PCA—mimic the skin’s own hydration system, helping it hold onto water and stay balanced from within.
Adding humectants like hyaluronic acid to your routine will restore your skin's healthy glow, minimize fine lines, and provide a plumping effect.

  • - + Nourishing
  • - + Skin Barrier Strengthening
  • - + Reduces Trans Epidermal Water Loss
  • - + Anti-Wrinkle
  • - + Plumping
  • - + Regenerating
  • - + Firming & Lifting
  • - + Anti-Pigmentation
  • - + Scar-Repairing
  • - + Brightening (Energising)
  • - + Antioxidant
  • - + Photo-Protecting
  • - + Micro-Needling Effect
  • - + Hydrating

Active Ingredients

  • - + Shea Butter
  • - + Glycoprotein of the Antarctic Microorganisms
  • - + Complex made from Prickly Pear Cactus extract and Jojoba oil
  • - + Cranberry Seed Oil
  • - + Walnut Extract
  • - + Complex of Hyaluronic Acid & Rhizobium
  • - + Cotton Oil
  • - + NMF (Natural Moisturising Factors)
Shea Butter

Shea Butter is renowned for its deeply nourishing benefits. It helps to repair and strengthen a weakened skin barrier while enhancing water retention. It quickly replenishes and restores dry, dehydrated and fragile skins.

Glycoprotein of the Antarctic Microorganisms

This Glycoprotein is made by microorganisms living in the harsh conditions of Antarctic glaciers. It prevents skin from drying, boosts collagen and elastin production, and helps keep the skin smooth and resilient. It reduces wrinkle depth and maintains the skin's integrity.

Complex made from Prickly Pear Cactus extract and Jojoba oil

This complex is formulated with Prickly Pear Cactus and Jojoba oil extracts, two plants known for their ability to survive and thrive in harsh environmental conditions. When applied to the skin, these extracts enhance cellular protection against environmental stressors such as sun exposure, temperature changes, pollution, and aesthetic procedures. By aiding cells in adapting to unfavourable conditions, the Complex protects against premature ageing and accelerates the skin repair processes.

Cranberry Seed Oil

Cranberry Seed Oil is rich in Vitamins C & E and essential fatty acids. All of which support a healthy skin barrier function and improve the skin healing processes. Additionally, it helps to enhance the hydration retention in the skin by preventing Trans epidermal Water Loss (TEWL), which is the loss of moisture through the skin.

Walnut Extract

Walnut Extract counteracts skin ageing by stimulating fibroblast activity and inhibiting elastase. Meaning that it prevents the natural elastin in our skin from degrading, promoting a more elastic and smoother skin, whilst reducing fine lines & wrinkles and promoting a more toned skin. This ingredient also has powerful antioxidant properties which prevents cells from oxidative stress.

Complex of Hyaluronic Acid & Rhizobium

The "Complex of Hyaluronic Acid & Rhizobium" contains a high molecular weight Hyaluronic Acid which is designed to remain on the surface of the skin, and forms a barrier to reduce Trans Epidermal Water Loss (TEWL). Whilst, the Rhizobium gel acts like a water reservoir, retaining all the hydration they have accumulated. The result is a newly formed water barrier, which is supple, flexible and non-comedogenic (does not clog pores).

Cotton Oil

Cotton Oil is extracted from cotton seeds. Naturally rich in Omega 6 & 9, two essential Fatty Acids that limit Trans epidermal Water Loss (TEWL) and strengthen the skin barrier. Cotton Oil is naturally rich in Vitamin E whose antioxidant properties protect cells from external damage and premature ageing.

NMF (Natural Moisturising Factors)

Natural Moisturising Factors are water-soluble substances which are naturally present in the epidermis. They are able to capture water and effectively hydrate the upper layers of the epidermis, making NMFs an incredibly hydrating ingredient for the skin.

  • - + Shea Butter
  • - + Glycoprotein of the Antarctic Microorganisms
  • - + Complex made from Prickly Pear Cactus extract and Jojoba oil
  • - + Cranberry Seed Oil
  • - + Walnut Extract
  • - + Complex of Hyaluronic Acid & Rhizobium
  • - + Cotton Oil
  • - + NMF (Natural Moisturising Factors)
Targeting Dry & Keratinised Skin

Dry and keratinised skin is a common condition where the skin becomes rough, flaky, and thickened due to an excessive build-up of dead skin cells. This can lead to discomfort, itching, and a dull, uneven appearance, making a tailored skincare routine essential to bring relief and restore your skin’s natural glow.

Dry and keratinised skin is often caused by a lack of moisture, environmental stress, ageing, and skin conditions like eczema. These factors can weaken the skin’s natural barrier, leading to increased roughness and a loss of that soft, supple feeling we all strive for. When the skin’s moisture levels are low, dead skin cells build up on the surface, creating a thick, rough texture.

Cold weather, low humidity, and harsh skincare products can exacerbate dryness, while ageing naturally slows down the process of shedding old skin cells. Conditions such as eczema further disrupt the skin barrier, intensifying the feeling of dryness and discomfort.

The key to managing this condition lies in replenishing lost moisture and gently exfoliating to remove dead cells. Hydration helps to soothe and plump the skin, while exfoliation reveals a smoother, healthier surface.

Combined, these steps help restore the skin’s natural barrier and improve overall texture. Taking care of dry and keratinised skin means embracing a routine of consistent hydration and gentle exfoliation.

Many people find that with regular care, their skin becomes noticeably more comfortable, less rough, and beautifully brighter. The right products work to soothe, soften, and repair, giving you back that smooth, resilient skin you deserve.

Caring for dry and keratinised skin is about more than just addressing a condition — it’s about nurturing your skin back to its best self. By combining hydration and exfoliation, you can transform your skin, soothing discomfort and boosting your confidence.

With the right care, your skin will feel softer, smoother, and visibly healthier. Embrace a dedicated skincare routine that meets your unique needs and enjoy the comfort and resilience of skin that looks and feels revitalised.

Clinical Proofs

USAGE TEST:
* This usage test lasted 3 weeks in an independent test centre, testing 20 women aged from 52 to 69
years old with dry to very dry skin.

- 100% of women believe their skin is nourished
- 100% of women observe that the driest zones in the face are moisturised
- 100% of women notice that the skin is moisturised
- 100% of women believe that the product prevents the skin from drying out
- 95% of women notice that the product relieves skin tightness
- 100% of women have a soft skin
- 90% of women have firmer skin
- 90% of women notice that their skin is revitalised
- 100% of women notice that their skin is protected

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Spotlight

Targeting Dry & Keratinised Skin

Dry and keratinised skin is a common condition where the skin becomes rough, flaky, and thickened due to an excessive build-up of dead skin cells. This can lead to discomfort, itching, and a dull, uneven appearance, making a tailored skincare routine essential to bring relief and restore your skin’s natural glow.

Dry and keratinised skin is often caused by a lack of moisture, environmental stress, ageing, and skin conditions like eczema. These factors can weaken the skin’s natural barrier, leading to increased roughness and a loss of that soft, supple feeling we all strive for. When the skin’s moisture levels are low, dead skin cells build up on the surface, creating a thick, rough texture.

Cold weather, low humidity, and harsh skincare products can exacerbate dryness, while ageing naturally slows down the process of shedding old skin cells. Conditions such as eczema further disrupt the skin barrier, intensifying the feeling of dryness and discomfort.

The key to managing this condition lies in replenishing lost moisture and gently exfoliating to remove dead cells. Hydration helps to soothe and plump the skin, while exfoliation reveals a smoother, healthier surface.

Combined, these steps help restore the skin’s natural barrier and improve overall texture. Taking care of dry and keratinised skin means embracing a routine of consistent hydration and gentle exfoliation.

Many people find that with regular care, their skin becomes noticeably more comfortable, less rough, and beautifully brighter. The right products work to soothe, soften, and repair, giving you back that smooth, resilient skin you deserve.

Caring for dry and keratinised skin is about more than just addressing a condition — it’s about nurturing your skin back to its best self. By combining hydration and exfoliation, you can transform your skin, soothing discomfort and boosting your confidence.

With the right care, your skin will feel softer, smoother, and visibly healthier. Embrace a dedicated skincare routine that meets your unique needs and enjoy the comfort and resilience of skin that looks and feels revitalised.

Clinical Proofs

Clinical Proofs

USAGE TEST:
* This usage test lasted 3 weeks in an independent test centre, testing 20 women aged from 52 to 69
years old with dry to very dry skin.

- 100% of women believe their skin is nourished
- 100% of women observe that the driest zones in the face are moisturised
- 100% of women notice that the skin is moisturised
- 100% of women believe that the product prevents the skin from drying out
- 95% of women notice that the product relieves skin tightness
- 100% of women have a soft skin
- 90% of women have firmer skin
- 90% of women notice that their skin is revitalised
- 100% of women notice that their skin is protected

* The above information has been supplied to the Embassy of Beauty by the brand manufacturer. Embassy of Beauty takes no responsibility for these claimed studies and or results.

Why I love it

  • "The efficacy of Biologique Recherche relies not only on its science-driven approach to balancing and curing the skin, but on its prescriptive and tailored nature."

    X Natalie K-F

    Founder, Embassy of Beauty

  • Biologique Recherche Creme Dermo-RL 50ml
    Biologique Recherche

    Creme Dermo-RL

    £222

    Biologique Recherche Creme Dermo-RL is a luxurious, rich cream that deeply nourishes and comforts very dry skin. It provides protection for those exposed to harsh weather and cold climates.

    Shea Butter provides the richest lipid nourishment in the formula, delivering a dense complex of fatty acids and phytosterols that deeply condition the skin, repair the barrier and relieve dryness and tightness.

    The Glycoprotein of the Antarctic Microorganisms prevents skin from drying, boosts collagen and elastin production and helps keep the skin smooth and resilient under environmental stress.

    A Complex made from Prickly Pear Cactus Extract and Jojoba Oil enhances cellular protection against environmental stressors including sun exposure, temperature changes and pollution, while improving the skin's capacity to retain moisture.

    Cranberry Seed Oil, Walnut Extract, the Complex of Hyaluronic Acid & Rhizobium and Cotton Oil complete the formula, delivering comprehensive hydration, antioxidant protection and barrier repair for a complexion that is visibly richer, more comfortable and lastingly moisturised.

    View product