Le Grand Serum
Benefits
Biologique Recherche Le Grand Serum is a powerful anti-ageing face oil. Its luxurious blend of 27 active ingredients slows cellular ageing, protects, firms and regenerates the skin, restoring radiance for a youthful complexion.
Telomeractiv — a breakthrough anti-ageing ingredient that protects telomeres, the protective caps at the ends of our chromosomes — helps maintain telomere length and the cells' capacity to divide and renew, producing a fundamental anti-ageing effect at the cellular level.
Yeast Extract supports a healthier microbial environment on the skin's surface and encourages gentle cellular turnover for a more refined and radiant complexion. Witch Hazel & St John's Wort Extract tone, firm and protect the skin with astringent and antioxidant plant actives.
Low Molecular Weight Hyaluronic Acid restores deep hydration and plumpness, while Myorelax Peptide, Beta-Glucan, Onion Myrrh & Myrtle Extract, White Tea Leaf Extract and Vitamin B3 (Niacinamide) collectively relax expression lines, soothe, brighten and strengthen the barrier, producing a measurably younger-looking, more luminous and comprehensively rejuvenated complexion.
Biologique Recherche Le Grand Serum is a powerful anti-ageing face oil. Its luxurious blend of 27 active ingredients slows cellular ageing, protects, firms and regenerates the skin, restoring radiance for a youthful complexion.
Telomeractiv — a breakthrough anti-ageing ingredient that protects telomeres, the protective caps at the ends of our chromosomes — helps maintain telomere length and the cells' capacity to divide and renew, producing a fundamental anti-ageing effect at the cellular level.
Yeast Extract supports a healthier microbial environment on the skin's surface and encourages gentle cellular turnover for a more refined and radiant complexion. Witch Hazel & St John's Wort Extract tone, firm and protect the skin with astringent and antioxidant plant actives.
Low Molecular Weight Hyaluronic Acid restores deep hydration and plumpness, while Myorelax Peptide, Beta-Glucan, Onion Myrrh & Myrtle Extract, White Tea Leaf Extract and Vitamin B3 (Niacinamide) collectively relax expression lines, soothe, brighten and strengthen the barrier, producing a measurably younger-looking, more luminous and comprehensively rejuvenated complexion.
Read less30 ml
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Is this for you?
For you if
- Wrinkles
- Loss of Firmness
- Loss of Volume
- Hyperpigmentation
- Damaged Barrier
- Dehydration
- Fine Lines
- Disrupted Microbiome
- Oily Skin
Suitable for
- Dehydrated Skin
- Oily Skin
- Dry Skin
- Balanced Skin
Not for you if
How to apply
Core Routine
- First Cleanse
- Second Cleanse
- Toner
- Hydrating Serum
- Targeted Serum
- Cream / Facial Oil
Period after opening
Extended Routine
- Eye Cleanse
- First Cleanse
- Second Cleanse
- Toner (Non-Exfoliating)
- Toner (Exfoliating)
- Mask
- Hydrating Serum
- Targeted Serum
- Eye Care
- Cream / Facial Oil
- SPF
Ingredients
TÈlomeractiv©Anti-Ageing · Regenerating · Skin Barrier Strengthening
TÈlomeractiv© is a breakthrough anti-ageing ingredient that protects telomeres, which are the protective caps at the ends of our chromosomes. These caps are crucial for maintaining healthy cell division. Every time cells divide, telomeres get shorter, which leads to cell ageing and eventual senescence (when cells stop dividing and functioning properly). TÈlomeractiv© helps maintain telomere length by providing important amino acids, peptides, and proteins needed for cell repair and activating telomerase, the enzyme that extends telomeres. Its antioxidant properties also reduce free radical damage, a major cause of telomere shortening. By supporting overall cell health, TÈlomeractiv© helps delay the signs of premature skin ageing.Low Molecular Weight Hyaluronic AcidPlumping · Hydrating
Low Molecular Weight Hyaluronic Acid (LMW-HA) is a smaller, more penetrative form of hyaluronic acid. Unlike high molecular weight forms that primarily hydrate the skin’s surface, LMW-HA has the ability to penetrate deeper into the epidermis, where it attracts and binds water to maintain optimal moisture levels from within. This deep hydration helps improve skin elasticity, firmness and smoothness, while reducing the appearance of fine lines. Additionally, it enhances overall suppleness, making the complexion look plumper and more resilient. It is ideal for dehydrated, dull or mature skin, and especially those in need of long-lasting hydration and improved texture.Myorelax PeptideInjectable Effect
The Myorelax Peptide is a type of a small peptide that effectively relaxes muscle tension and inhibits micro-contractions, offering a gentle and non-invasive alternative anti-wrinkle injectables. This action reduces the depth and length of expression lines and wrinkles, providing a filling and smoothing effect.Beta-GlucanSkin Barrier Strengthening · Anti-Wrinkle · Plumping
Beta-glucan, derived from yeast, is a chain of sugar molecule known for its humectant (hydrating), collagen-boosting, and anti-inflammatory properties. It strengthens the skin barrier, supports a balanced microbiome, and enhances resilience against environmental aggressors. Beta-glucan deeply hydrates the skin, diminishes wrinkles, and provides a soothing effect, making a great multi-benefit ingredient for all skin types.Onion, Myrrh & Myrtle ExtractPurifying · Sebum Regulating · Antioxidant
Unique to Biologique Recherche, the "Complex of Onion, Myrrh & Myrtle" has incredible astringent (tightening), purifying, antioxidant and soothing properties; which is very effective for an oilier complexion combatting sebum-regulation, acne or congestion.
View full ingredient list
Smell & Texture
Delivery & Returns
ROYAL MAIL TRACKED 48:
£5.00 (free for members on orders over £75)
Delivered within 2-3 working days.
NEXT WORKING DAY DELIVERY:
£8.00 (free for members on orders over £150)
Delivered the next working day if ordered before 1pm.
SATURDAY UK DELIVERY:
£18.00
Delivered on Saturday when ordered before 1pm on Friday.
*(For NI, Channel Islands & Scotland - due to the courier service in place, we cannot guarantee next day delivery to these areas, however we expect you will receive your delivery within 2-5 days).
RETURNS
Items returned by post can take up to 14 working days to process. Credit notes can be applied to your account within 5 working days. For refunds, we will reimburse you using your original payment method which can take up to 14 days.
GET THE SET
La Grande Creme + Le Grand Serum
The Benefits
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Anti-Ageing (Epigenetics)
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Regenerating
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Skin Barrier Strengthening
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Anti-Wrinkle
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Firming & Lifting
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Plumping
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Scar-Repairing
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Hydrating
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Injectable Effect
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Microbiome Balancing
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Anti-Inflammatory
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Purifying
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Sebum Regulating (Mattifying)
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Antioxidant
Anti-Ageing (Epigenetics)
Regenerating
Skin Barrier Strengthening
Anti-Wrinkle
Firming & Lifting
Plumping
Scar-Repairing
Hydrating
Injectable Effect
Microbiome Balancing
Anti-Inflammatory
Purifying
Sebum Regulating (Mattifying)
Antioxidant
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+
Anti-Ageing (Epigenetics)
-
-
+
Regenerating
-
-
+
Skin Barrier Strengthening
-
-
+
Anti-Wrinkle
-
-
+
Firming & Lifting
-
-
+
Plumping
-
-
+
Scar-Repairing
-
-
+
Hydrating
-
-
+
Injectable Effect
-
-
+
Microbiome Balancing
-
-
+
Anti-Inflammatory
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-
+
Purifying
-
-
+
Sebum Regulating (Mattifying)
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+
Antioxidant
Spotlight
Epigenetics Science
Clinical Proofs
Clinical Proofs
Frequently Asked Questions
Where do I use this oil in my routine?
How often should I use this oil?
Can I use this oil instead of a cream?
Can I use this oil if I have oily skin?
Can I use this oil if I have dry skin?
Can I use this oil if I have sensitive skin?
Can this product be used pregnancy/breast feeding?
Does it contain allergens?
Is the packaging recyclable?
Is this product fragrance-free, cruelty-free, vegan-friendly?
Why I love it
X Natalie K-F
Founder, Embassy of Beauty





